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15th Feb 2018

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Mimicking the fat cell microenvironment in vitro

Adipose tissue is vitally important to various normal processes of the human body, and it has also many implications...

+HCS, HCA & Biology

13th Feb 2018

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Invasion of Staphylococcus aureus on human keratinocytes : from animals to humans

A staphylococcal infection is a common bacterial skin infection due to staphylococci bacteria. Staphylococcus aureus (S aureus) is part of the nasal...

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01st Feb 2018

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3D in Vitro Cell Culture: Mainstream in Drug Discovery and Drug Repositioning

Half of all drugs fail in Phase II and Phase III clinical trials due to a lack of efficacy...

+HCS, HCA & Biology

30th Jan 2018

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Cellular seismology : the use of vibrations to map the inside of cell

There are many ways to look cells and inside components. At HCS Pharma we know well fluorescent microscopy in...

+english

25th Jan 2018

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Biomimetic Materials: In vivo-like 3D cell culture models

A review of biomaterials technologies for 3D cell culture

+english

23rd Jan 2018

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Studying sprouting angiogenesis and vascular permeability in a 3D human in vitro model

Yukiko Matsunaga and Fabrice Soncin have developed a human microvessel-on-a-chip that allows to study pro- and anti-angiogenic effects of...

+english

18th Jan 2018

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Drug discovery : Need of reliable IVIVE for pharmacodynamics and pharmacokinetics assessment

For ethical and cost-related reasons, use of animals for the assessment of mode of action, metabolism and/or toxicity of...

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16th Jan 2018

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Winner of 2017 Photomicrography Competition from Nikon’s Small World

Sometime the beauty is just under our eyes, as you can see with this amazing picture of a “ordinary” skin...

+HCS, HCA & Biology

08th Jan 2018

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Targeting extracellular matrix mechanics as therapeutic approach

Extracellular matrix is a key point to find new therapeutic drugs

+english

02nd Jan 2018

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Internal forces directing cell migration are revealed by live-cell microscopy

How to see cells moves ?

+HCS, HCA & Biology

21st Dec 2017

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3D-printed minifactories at ETH Zurich

A new ink with live bacteria is developed at ETH

+english

13th Dec 2017

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New Technique Visualizes Whole Cells at Super-Resolution

DNA-PAINT + confocal technologies = amazing pictures!

+english

07th Dec 2017

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2D vs 3D-induction of neuronal cells : who wins ?

In a study published last October in the journal Stem Cell Research, Chandrasekaran et al. compared the induction of...

+english

20th Nov 2017

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We were at “HCS plateforms day” of the the French Agency For Food and Safety

Last friday (10/11), we presented our neurotoxicity and genotoxicity assays at the French Agency for Food and Safety (ANSES)

+english

08th Nov 2017

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Carl Zeiss Campus : a world of knowledge about microscopy

The Carl Zeiss campus website is just a treasure ! Discover it !

+english

17th Oct 2017

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Are you going to Cosmetic 360 ? We will be present !

Are you interested by automated cellular imaging and image analysis in dermocosmetology ?

+francais

29th Sep 2017

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To build and visualize 3D pictures : An important task for our CDO !

culture + acquisition + analyse + visualization ... in 3D !

+english

27th Sep 2017

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microRNA expression in human primary cells: an atlas

The first extensive atlas of microRNA expression in human primary cells !

+english

24th Aug 2017

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Assessing GPCRs signaling using fluorescent bioscensors

Near half of the current drugs target GPCRs signaling !

+english

10th Aug 2017

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Quantitative mRNA imaging in a small yet entire brain

RNA fluorescence in situ hybridization (FISH)

+francais

13th Jul 2017

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La Donnée : l’ADN des sciences de la vie

De l'importance des données dans les sciences de la vie

+english

26th Jun 2017

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The Top 10 Trends Shaping the Future of Pharma

New trends in Pharma

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15th Jun 2017

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Smooth 2D manifold extraction from 3D image stack in Nature Communications

3D to 2D reduction with maximum accuracy