Many categories of drugs can induce hepatotoxicity, so improving the prediction of toxic drugs is important. In vitro models using human hepatocytes are more accurate than in vivo animal models. Good in vitro models require Read more…
Cells have diverse circuitry to sense and respond to extrinsic metabolic signals. Extracellular matrix (ECM) reorganization which is central to both tissue expansion and regeneration. ECM remodeling is also a signature of pathological processes, such Read more…
It is a great pleasure for us to welcome a new member in our scientific advisory board, Dr Samuel Meignan! He will for sure help us to develop relevant models related to oncology therapeutic area. Read more…
I was really pleased to participate in the kick-off meeting for the launch of NanoSTEM project, a European Marie Skłodowska-Curie Innovative Training Network (ITN) project, this summer. NanoSTEM is a multidisciplinary and innovative project including 11 Read more…
Every year around 10 millions of animals are used to assess compound’s safety, with a total cost estimated to 3 billions euro. Despite animal testing is mandatory by OECD to guarantee consumer safety, toxicologists are Read more…
The skin performs important function, including sun protection. Melanin distribution in the epidermis plays a role in photoprotection. Solar radiations induced epidermal DNA damages, mostly in the basal layer, and is an established caused of Read more…
“Regulation needs to catch up with innovation.” Henry Paulson – CEO Goldman Sachs A very nice state of art about animal testing and its alternatives can be found in the new article “Animal Testing and its Read more…
Melanoma is a type of skin cancer that develops from cells called melanocytes, is one of the fastest-growing and deadliest cancer in the world. It usually caused by DNA damage resulting from exposure to ultraviolet Read more…
Last week, HCS Pharma had the pleasure to attend to COSM’ING 2018 for their 20th anniversary which took place in the Palais du Grand Large at Saint Malo from the 4th to 6th July ! Read more…
In a recent article, Dr Antony Orth from the Australian Research Council’s, Centre of Excellence for Nanoscale BioPhotonics (CNBP) explains how to use the photobleaching phenomenon to increase the potential of fluorescence microscopy. The BAMM technique (bleaching-assisted Read more…
Last week we had the pleasure to attend the first SLAS Europe (Society for Laboratory Automation and Screening) meeting, which took place in the great Brussels Square meeting centre (Belgium) between the 27th and the Read more…
HCS pharma has organized its second scientific advisory board! We were pleased to gather around the table (physically or via a Webex visioconference for those who could not make the trip) David Devos, Roméo Cecchelli, Read more…
We are pleased to announce for our US customers that BIOMIMESYS® Hydroscaffold are available for direct sale at our distributor Iwai North America Inc. Thank you again for your previous orders and for your trust in HCS Read more…
Since the liver is responsible for the selective uptake, metabolism and excretion of xenobiotics, this organ is highly predisposed to drug-induced toxicity: this essential function is the primary reason for the failure of pharmaceuticals during Read more…
We are pleased to announce the launch of our new page dedicated to nutraceuticals! We have developed four assays to confirm the efficacy of nutraceuticals on human and animal cells. Our assays are based on Read more…
Meeting us at SLAS Europe 2018, on Wednesday 27th & Thursday 28th of June on Molecular Device Booth (#401) at the Square Brussels Meeting Centre, Brussels, Belgium.
We had the pleasure to attend ELRIG Fr meeting in Bischoffsheim (near Strasbourg) on the 23-24th of May. There we enjoyed meeting our partners Molecular Devices and Integra biosciences, and seeing great presentations about the Read more…
Researchers from the Department of Dermatology of the University of California have a commensal strain of Staphylococcus epidermidis that protects against skin neoplasia. This strain produces 6-N-hydroxyaminopurine (6-HAP), a molecule that inhibits DNA polymerase activity. Mice colonized with Read more…
Interesting paper from Christian Dani team about the potential of Brown and brown-like adipocytes (BAs) proginitors derived from hiPSCs to dissipate energy stored and the promising potential to treat obesity and metabolic disorder. In this Read more…
Thank to our partner Integra Biosciences, we are happy to present you an application note about a straightforward workflow for 3D cell seeding and spheroid formation using HCS Pharma’s BIOMIMESYS® plates in combination with INTEGRA’s VIAFLO 96/384 Read more…
As you should know, the GDPR (General Data Protection Regulation) is now a reality and every companies in Europe has to be “compliant” with it. Of course we’re updating our privacy policy (soon) but, in HCS Read more…
Last week, we attended to the 6th edition of COSMED Meeting in the west of France. We would like to thank the organisation team of COSMED for giving us the opportunity to attend to this event. Read more…
Our new poster on BIOMIMESYS® technology is now avalaible on this link. It presents the use of this scaffold on our automated platform (Hapix), with the development of a 3D cell model for steatosis and phospholipidosis Read more…