A staphylococcal infection is a common bacterial skin infection due to staphylococci bacteria. Staphylococcus aureus (S aureus) is part of the nasal microbiome and is the most important of these bacteria in human diseases. About 15–40 per cent of healthy humans are carriers of S aureus, and staphylococcal infection has become a significant public health burden due to infection with antibiotic resistant strains, including methicilin resistant S. aureus (MRSA).
In a recent paper, Hau et al. have study the ability of swine isolated MSRA strain to adhere to human keratinocyte. Compared to a human isolated MSRA, the swine strain adhered equivalently to human keratinocytes in vitro and contained the same genes related to adherence ability. This study showed the high degree of similarity in adherence mechanism thought different S. aureus species, highlighting the need to have a cross species model to study bacterial infection on skin models.
Source : Methicillin-Resistant Staphylococcus aureus SequenceType (ST) 5 Isolates from Health Care and Agricultural Sources Adhere Equivalently to Human Keratinocytes. in Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02073-17. doi: 10.1128/AEM.02073-17. Print 2018 Jan 15
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