Whether in the analytical or in the production field, quality and homogeneity of culture media batches in the course of time has a real impact in laboratories. These media may include more than 300 components including proteins, lipids, as well as hormones, and other molecules. Moreover, their cost has a real impact on the budgeting of research projects.

Find out in this article from Genenenws.com the challenges of producing alternatives complex environments to replace serum in the case of the production of biosimilars (either during the production or at the moment of purification).
This problems occurring also in cell cultures laboratories, some companies are seeking to develop alternatives to serums, reproducing as faithfully as possible biological activity …

Source: http://www.genengnews.com/gen-articles/on-the-money-cell-culture-optimization/5771/