FANTOM, an international scientific consortium led by RIKEN, has now created the first extensive atlas of microRNA expression in human primary cells. Leveraging the collection of RNA samples established as part of the fifth edition of FANTOM, the team has sequenced microRNA libraries of hundreds of human samples, including many cell types for which the microRNA presence had never been investigated before.
More information: An integrated expression atlas of miRNAs and their promoters in human and mouse, Nature Biotechnology (2017). DOI: 10.1038/nbt.3947
The atlas is available at fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/
By using in situ hybridization, HCS Pharma is able to stain microRNA on cell cultures and FFPE (Formalin-fixed, paraffin-embedded) histology sections, for an in situ visualization, localization, and quantification.