HCS, HCA & Biology
How to study cholestasis in 3D cultures by cellular imaging
Since the liver is responsible for the selective uptake, metabolism and excretion of xenobiotics, this organ is highly predisposed to drug-induced toxicity: this essential function is the primary reason for the failure of pharmaceuticals during drug development (Ref 1.). Cholestatic and hepatocellular injuries are two of the most severe manifestations of Read more…