The comet assay is a sensitive, well established technique for quantifying DNA damage in eukaryotic cells.
Poster – Use of Automated High Content Analysis Applied To Assessment Of Primary DNA Damages With γH2AX and Comet Assays
Quantifying DNA damage is mandatory to assess potential adverse effects of candidate, drugs, molecules or extracts developed in dermo-cosmetic industry. Different assays can be performed to detect primary DNA damages, such as γH2AX or the single cell gel electrophoresis also known as the comet assay.
Quantifying DNA damage is mandatory to assess potential adverse effects of candidate drugs or molecules or extracts developed in the dermo-cosmetic industry, but also to assess the efficacy of therapeutic approaches with the aim of producing tumor cell genotoxicity in cancer treatment.