La carte de la Cosmetic Valley

HCS Pharma is now member of the Cosmetic Valley competitiveness cluster, the worldwide leader in perfumery and cosmetics resources, skills, research and training.

Cosmetic Valley was designated a “competitiveness cluster” by the Inter-ministerial Committee for the Development and Competitiveness of Regions (CIACT) on July 12, 2005. Today it is the worldwide leader in perfumery cosmetics resources and contributes to the development of the perfumery cosmetics sector with more then 800 companies for approximately 70,000 jobs and €11 billion in revenue !

With the backing of local authorities, Cosmetic Valley leads a network of businesses and research and training centres committed to a joint approach based on a dynamic focused on innovation.

HCS Pharma is really happy to be now part of this cluster, as our dermocosmetology services are focused on innovation and new efficient technologies (like HCS). It’s a pleasure to meet and talk with researchers of the cosmetology field.

Julian, our COO, will be present at the Cosmetic 360 event tomorrow, wednesday the 17th of October, in Paris.

This international innovation fair for perfumery and cosmetics industry will be held at Carousel du Louvre. Julian will be glad to meet you there and discuss about the benefits provided by automated cellular imaging and image analysis done on your tissue slides and in vitro cell cultures.

Cell biology is part of the R&D activity in dermocosmetology, as providers of active extracts or pure compounds have to demonstrate their efficacy and safety. At HCS Pharma, we are developing new dermocosmetology assays on relevant cellular models, like human primary keratinocytes and human primary fibroblasts, using our automated platform and high content analysis system. Through the use of 96 or 384 wells plates combined with process automation, we constantly increase the throughput in order to allow proof of concept assays of one or several compounds up to the screening of large compounds libraries, for single endpoint or live cells analysis to multiplexed phenotypic screening.
Assessment of compounds activity/safety can be performed on several parameters in parallel with a multiplexed assay. Among them, we describe here wound healing, inflammation assay & extra cellular matrix analysis, which are routinely performed. Other parameters can be analysed on demand on live and fixed cells, using chemical probes or immunocytochemistry.

View and download on Slideshare (low quality) : https://www.slideshare.net/hcspharma/in-vitro-dermocosmetology-high-content-analysis-approach-using-human-primary-keratinocytes-and-fibroblasts

Ask for high quality link  by putting your email below

Cell biology is part of the R&D activity in dermocosmetology. At HCS Pharma, we are developing new democosmetology assays on human primary keratinocytes using our automation plateform and high content analysis suite.

Assessment of compounds activity/safety can be performed on several parameters (wound healing, hydration, inflammation, toxicity, genotoxicity). Further parameters could be analyzed on demand using probes and immunocytochemistry.

Thought the use of high content analysis technologies, we can provide a wide range of results from phenotypes quantification cell by cell to live cells imaging movies.

View and download on Slideshare (low quality) : http://fr.slideshare.net/hcspharma/in-vitro-dermocosmetology-high-content-analysis-approach-using-human-primary-keratinocytes

Ask for high quality link  by putting your email below

Cell biology is part of the R&D activity in dermocosmetolgy. At HCS Pharma, we are developing dermocosmetology assay using our automation platform and high content analysis software.

Wound healing is a complex process resulting in new tissue formation, and skin remodeling. We have developed an in vitro automated assay in 96 well-plate using human primary epithelial keratinocytes in order to avoid expensive used of animal models, reduce the cost of assay and increase the volume of compounds tested.

This assay, also called “The scratch assay” is relevant to evaluate the efficacy of active ingredients for irritated skins as well as for stretch marks. In dermocosmetology, this assay is commonly used to assess compounds efficiency on wound healing process.

aquaporinewound-healing

If you want to know more on this assay, follow this link to our page on the website or contact us!

 

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