HCS, HCA & Biology
How phenotypic screening could help to predict DILI ?
HCS/HCA is a great way to predict drugs toxicity
HCS/HCA is a great way to predict drugs toxicity
The creation of a double strand break (DSB) is accompanied by the phosphorylation of histone H2AX. The measurement of serine 139 phosphorylated histone H2AX (γH2AX) is reported to be a marker of interest to identify potential genotoxic activity.