RNA fluorescence in situ hybridization (FISH)
Researchers from Yale university presented a new technology to increase presicion of high speed (and wide field) imagery. Using both LEDs and laser light, they minimize spacial coherence and granularity. It's a promising way to optimize cells imaging.
Here is a nice example of cell imaging uses for stem cells characterisation. Different culture conditions are performed on adult stem cells and cell adhesion, proliferation, survival, and cell migration are followed by cell imaging.