Our CEO, Nathalie, participated last month at the 2015 edition of the “Femmes de l’économie” contest for the west of France. We are happy to announce that she won the innovation technology prize. We prepare now the national contest, which taking place at the end of november at the french national assembly in Paris.

Here is the interview of Nathalie (in french)

FDE2015

Cardiotoxicity analysis of compund is often performed in a later phase during developement. Now, with cell imaging, cardiotoxicity assay can be performed in vitro in higher throughput and thus this assay can be used in the early phase of research. In this article, they explained how to do the automation in an unbiased way the Video-Based Analysis of Contractility and Calcium Flux of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultures.

Curated from Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales

HCA/HCS assays are now realised on cell models which are more and more complex as 3D and/or co-culture. And to be more relevant, imaging assay in low/medium troughput can also be performed on whole organism as zebrafish. Here is an interesting video from Department of Biological Sciences, University of Notre Dame, explaining how to do imaging on zebrafish embryos.

The zebrafish is an excellent experimental organism to study vertebrate developmental processes and model human disease. Here, we describe a protocol on how to perform a manual high-throughput chemical screen in zebrafish embryos with a whole-mount hybridization (WISH) read-out.

Curated from www.jove.com

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