The human skin microbiota could promote wound healing

Skin commensals are crucial in the maintenance of the epithelial barrier function, regulation of the host immune system, and prevent invasion of other pathogenic microbes.        In this article, published in September 2018, Burmeister et al show that Staphlylococcus, Streptococcus, Pseudomonas, Corynebacterium, and anaerobes have both beneficial and harmful effects depending Read more…

Predicting clinical outcomes of wound healing assessment : the limitations of the mice model

Wounds can exhibit impaired healing, as a consequence of pathologic failure to process one of the normal stage of healing. Wound healing impairment could be characteristic of the treatments of chronic wounds due to immobilisation, diabetes, and skin infection. Characterization of compounds efficacy on wound healing parameters is important dermato Read more…

Poster – High Content Screening of automated wound healing and cytotoxicity assays in 2D and 3D culture

To find anti-cancer drugs, different cellular modifications can be looked at: cell death effect on proliferating cells either in 2D culture or on spheroids (3D culture), anti-mitotic, anti-migration/invasion, anti-angiogenesis effects… Different assays can be performed to follow these different effects. High content screening is a multi-parametric technology allowing searching for poly-effects drugs.