Cell biology is part of the R&D activity in dermocosmetology. At HCS Pharma, we are developing new democosmetology assays on human primary keratinocytes using our automation plateform and high content analysis suite.

Assessment of compounds activity/safety can be performed on several parameters (wound healing, hydration, inflammation, toxicity, genotoxicity). Further parameters could be analyzed on demand using probes and immunocytochemistry.

Thought the use of high content analysis technologies, we can provide a wide range of results from phenotypes quantification cell by cell to live cells imaging movies.

View and download on Slideshare (low quality) : http://fr.slideshare.net/hcspharma/in-vitro-dermocosmetology-high-content-analysis-approach-using-human-primary-keratinocytes

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Cell biology is part of the R&D activity in dermocosmetolgy. At HCS Pharma, we are developing dermocosmetology assay using our automation platform and high content analysis software.

Wound healing is a complex process resulting in new tissue formation, and skin remodeling. We have developed an in vitro automated assay in 96 well-plate using human primary epithelial keratinocytes in order to avoid expensive used of animal models, reduce the cost of assay and increase the volume of compounds tested.

This assay, also called “The scratch assay” is relevant to evaluate the efficacy of active ingredients for irritated skins as well as for stretch marks. In dermocosmetology, this assay is commonly used to assess compounds efficiency on wound healing process.

aquaporinewound-healing

If you want to know more on this assay, follow this link to our page on the website or contact us!

 

This summer has been very studious for us with the development and validation of new tests in the oncology field. Cytotoxicity assay has been developed in 2D and 3D culture in 96 well-plates as well as wound healing assay on different cell lines. Few examples are presented in this website page “Cytotoxicity in 2D & 3D culture” and scratch assay (wound healing). And to know more on this assay, don’t hesitte to contact us.

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