Thomas Kirchhausen, Eric Betzig et al. publish an article in Sciences about SIM (structured illumination microscopy) and the observation of moving molecules inside cells. The incredible spatial and time resolution give the opportunity to see for exemple proteins which pass the cell membrane.
On the surface of a living cell at any given time, hundreds of tiny bubbles are popping into existence, surrounding and incorporating proteins, hormones, fats, and the occasional bacteria or virus. But until now the details of this activity were inferred – you couldn’t actually see it.
Li et. al., “Extended Resolution Structured Illumination Imaging of Endocytic and Cytoskeletal Dynamics,” Science.
Aditional informations : Imaging Techniques Set a New Standard for Super-Resolution in Live Cells