Poster – A groundbreaking 3D cell culture technology for HCS: BIOMIMESYS hydroscaffold

Most potential drug candidates (90%) fail within the clinical trials, mainly because of lack of efficacy. What if the pharmaceutical industry uses predictive human in vitro models in early drug discovery ? View and download on Slideshare (low quality) https://fr.slideshare.net/hcspharma/a-groundbreaking-3d-cell-culture-technology-for-hcs-biomimesys-hydroscaffold Ask for high quality link by putting your email below

Poster – Characterisation of 3D cultured primary human hepatocytes and HepaRG for DMSO-free preclinical toxicity testing

Hepatocytes in primary cultures are still the gold standard in the pharmaceutical industry ; however they are expensive and have a very short lifespan with a progressive loss of specific functions over time. The dipolar aprotic solvent, dimethyl sulfoxide (DMSO) is wildly used to stabilize the liver specific function of Read more…

BAMM technique. Credit: CNBP

Photobleaching, a great advantage in super-multiplexed fluorescence microscopy!

In a recent article, Dr Antony Orth from the Australian Research Council’s, Centre of Excellence for Nanoscale BioPhotonics (CNBP)  explains how to use the photobleaching phenomenon to increase the potential of fluorescence microscopy. The BAMM technique (bleaching-assisted multichannel microscopy) takes advantage of the rate of photobleaching to identify a fluorophore (instead of Read more…

Ce microscope permet d’observer des cellules vivantes avec des détails impressionnants !

Nous sommes toujours fascinés par les développements de l’imagerie, en particulier les prises de vues en 3D (qui sont au cœur de notre métier). Dans cette article, l’équipe combine la technologie des feuillets de lumière avec l’optique adaptative utilisée normalement en astronomie. Impressionnant ! Pour la première fois, des scientifiques Read more…

Discover our new application note made with Integra Biosciences about HCS and 3d cell culture

Thank to our partner Integra Biosciences, we are happy to present you an application note about a straightforward workflow for 3D cell seeding and spheroid formation using HCS Pharma’s BIOMIMESYS® plates in combination with INTEGRA’s VIAFLO 96/384 pipetting system and without forgetting to mention with the use of our imageXpress micro confocal Read more…