We are really happy to be a part of the britany women’s network “Femmes de Bretagne”. This network aim to empower women who want to create companies, with kindness and respect.
We are very proud to contribuate to organize next ELRIGfr in Rennes. The central topic will be “Lab Automation, Formulation & Phenotypic screening”
« Phenotypic Drug Discovery with High Content Screening » by Permin Elmer
Our CEO, Nathalie, participated last month at the 2015 edition of the “Femmes de l’économie” contest for the west of France.
To find anti-cancer drugs, different cellular modifications can be looked at: cell death effect on proliferating cells either in 2D culture or on spheroids (3D culture), anti-mitotic, anti-migration/invasion, anti-angiogenesis effects… Different assays can be performed to follow these different effects. High content screening is a multi-parametric technology allowing searching for poly-effects drugs.
In this article, authors emphasize the importance of standardisation in the development of HCS.
Thomas Kirchhausen, Eric Betzig et al. publish an article in Sciences about SIM (structured illumination microscopy) and the observation of moving molecules inside cells. The incredible spatial and time resolution give the opportunity to see for exemple proteins which pass the cell membrane.
We just begin a test period of the Operetta “High Content Imaging System” from Perkin Elmer. First impressions are very goods, especially using confocal option for 3D imaging.
Vas Narasimhan, global head development at Novartis Pharmaceuticals talks about the importance of digital nowadays in pharmaceutical companies. He also emphasis the need to combine different cells therapies to efficiently cure complex diseases. Of course for us, it’s also a confirmation of HCS future developments to test the efficiency of these combinations.
It was a pleasure for us to welcome Antoine at HCS Pharma for a 6 week internship focused on statistics interpretation improvement.
After a license degree in Cellular Biology and physiology Méryl Roudaut is currently studying for his second year of master degree at Université Paul Sabatier (UPS) Toulouse III
Aviv Regev at the Broad Institute, in Cambridge, use fluidic systems to separate cells and submits them to detailed genetic analysis, at the rate of thousands per day. The goal is to build a comprehensive cellular atlas of the human, based on gene expression profile.
As we are a active part of Frenchtech mouvement in Rennes, we also participate to the french startup assembly.
Our partner CELENYS has been awarded at Forum Labo 2015 with the innovation price for Biomimesys®.
Last week, we were very pleased to meet the french team for Dell worldwide program “Center for Entrepreneurs”
Researchers from Yale university presented a new technology to increase presicion of high speed (and wide field) imagery. Using both LEDs and laser light, they minimize spacial coherence and granularity. It’s a promising way to optimize cells imaging.
We are no proud member of “La Cantine Rennes” who lead the FrenchTech initiative in Rennes. At the crossroad of IT, biotechnology and Big Data, we are honored be a part of the entrepreneurship spirit in Rennes, in Brittany and in France. “La French Tech” refers to all the people Read more…
We are happy to announce that work is in constant progress. Just before the beginning of this promising new year, we have completed the production of our cell working bank and the first steps of our R&D projects. In particular, among other tests, we are now able to do automated Read more…
