Atopic dermatitis (AD) is a chronic, common inflammatory skin disease affecting 15-20% of children and 1-3% of adults worldwide. Loss of bacterial diversity from excess abundance of Staphylococcus aureus is associated with increased disease severity, nevertheless, how dysbiosis of the skin microbiome may influence atopic dermatitis pathophysiology is unknown. In Read more…
Many skin diseases, including psoriasis and basal cell carcinoma, are associated with microbial dysbiosis characterized by reduced C. acnes prevalence. C. acnes is a facultative anaerobic bacterium that is frequently found on the human skin. This bacterium is both an opportunistic pathogen and a commensal organism. Indeed, most individuals are Read more…
Wound healing is a crucial physiological process rehabilitating the unity of the skin barrier. Inflammation in wound healing is a weapon with two edges. It is indispensable but must be strongly regulated both temporally and spatially. In this recent study, Li et al. show skin commensal S. epidermidis produces a Read more…
The skin is inhabited by Bacteria, archaea, fungi and viruses, collectively referred to as the skin microbiota. These commensals serve as first line of defense at the skin surface and play a vital role in both the establishment and maintenance of the skin’s immune system. Among the bacteria, some of Read more…
Skin commensals are crucial in the maintenance of the epithelial barrier function, regulation of the host immune system, and prevent invasion of other pathogenic microbes. In this article, published in September 2018, Burmeister et al show that Staphlylococcus, Streptococcus, Pseudomonas, Corynebacterium, and anaerobes have both beneficial and harmful effects depending Read more…
Melanoma is a type of skin cancer that develops from cells called melanocytes, is one of the fastest-growing and deadliest cancer in the world. It usually caused by DNA damage resulting from exposure to ultraviolet (UV) light from the sun. P. acnes is a ubiquitous gram-positive anaerobic bacterium present in Read more…