The first extensive atlas of microRNA expression in human primary cells !
Near half of the current drugs target GPCRs signaling !
RNA fluorescence in situ hybridization (FISH)
More than 300,000 images available !
How cellular imaging and image analysis can be used !
3D cell models are now attracting a huge interest from scientists working both on toxicity and pharmacology assay development. They are considered more relevant at mimicking the in vivo situation. However, phenotypic assays on these models can be challenging, and are at least more complex.
3D spheroids are more and more used in High Content Screening
Despite continuous improvement of DNA FISH, a method that has been extensively used for years, it still requires harsh treatments to allow probe hybridization.
The first place has been won by Dr. Oscar Ruiz
HCS Pharma a reçu l’agrément CIR (Crédit Impôt Recherche) du Ministère de L’Enseignement Supérieur et de la Recherche. Cette accréditation signe la reconnaissance par l’administration française de notre capacit
Lattice light-sheet microscopy: spatiotemporal resolution high enough to follow fast, nanoscale dynamic processes
This new microscopy technology is a promising tool for in vivo 3D imaging of fast dynamic processes in cells and embryos. Lattice light-sheet microscopy allows fast 3D superresolution, with lower photobleaching and phototoxicity.