HCS, HCA & Biology
Biomimetic Materials: In vivo-like 3D cell culture models
A review of biomaterials technologies for 3D cell culture
HCS, HCA & Biology
Drug discovery : Need of reliable IVIVE for pharmacodynamics and pharmacokinetics assessment
For ethical and cost-related reasons, use of animals for the assessment of mode of action, metabolism and/or toxicity of new drug candidates has been increasingly scrutinized in research and industrial applications. Physiologically based pharmacokinetic (PBPK2) modeling is the most potent in silico tool used for extrapolation of pharmacokinetic parameters to Read more…