Cardiotoxicity analysis of compund is often performed in a later phase during developement. Now, with cell imaging, cardiotoxicity assay can be performed in vitro in higher throughput and thus this assay can be used in the early phase of research. In this article, they explained how to do the automation in an unbiased way the Video-Based Analysis of Contractility and Calcium Flux of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultures.
The extracellular matrix (ECM) is the non-cellular component of tissue. Its composition and structure can vary between different tissues. The ECM transmits biochemical and biomechanical cues to the cells within it, ensuring tissue homeostasis. The Read more…
Few weeks ago, the Hong Kong–based company Insilico Medicine announced the beginning of a phase 1 clinical trial concerning a potential therapy for idiopathic pulmonary fibrosis. The event might have gone unnoticed but the way Read more…
The skin microbiota refers to the microorganisms living on the skin, on the surface of the epidermis, but also in the dermis and the hypodermis (Nakatsuji et al., 2013). On 1 cm2 of human skin, Read more…
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