Cardiotoxicity analysis of compund is often performed in a later phase during developement. Now, with cell imaging, cardiotoxicity assay can be performed in vitro in higher throughput and thus this assay can be used in the early phase of research. In this article, they explained how to do the automation in an unbiased way the Video-Based Analysis of Contractility and Calcium Flux of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultures.
The skin microbiota refers to the microorganisms living on the skin, on the surface of the epidermis, but also in the dermis and the hypodermis (Nakatsuji et al., 2013). On 1 cm2 of human skin, Read more…
Oxidative stress is a pathological state characterized by a cellular submergence by Reactive Oxygen Species (ROS) such as free radicals. ROS are naturally produced in small quantities by the cellular metabolism and used in physiological Read more…
The extracellular components of the skin can be divided into fiber-forming structural molecules, nonfiber-forming structural molecules, and “matricellular proteins”. Optimal quantities of different matrix components and their delicate interactions are necessary to maintain normal physiologic Read more…
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