Cardiotoxicity analysis of compund is often performed in a later phase during developement. Now, with cell imaging, cardiotoxicity assay can be performed in vitro in higher throughput and thus this assay can be used in the early phase of research. In this article, they explained how to do the automation in an unbiased way the Video-Based Analysis of Contractility and Calcium Flux of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultures.
In the brain, we have about 100 billion of neurons but they represent only 10 to 50% of the total cells (von Bartheld et al., 2016). Indeed, glial cells, including astrocytes, oligodendrocytes and microglia are Read more…
The extracellular matrix (ECM) is the non-cellular component of tissue. Its composition and structure can vary between different tissues. The ECM transmits biochemical and biomechanical cues to the cells within it, ensuring tissue homeostasis. The Read more…
Few weeks ago, the Hong Kong–based company Insilico Medicine announced the beginning of a phase 1 clinical trial concerning a potential therapy for idiopathic pulmonary fibrosis. The event might have gone unnoticed but the way Read more…
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