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Since last year, our PhD student Véronique De Conto has been working on the impact of microenvironment in cerebral in vitro model. On the supervision of our study director Dr. Elodie Vandenhaute and her thesis director Pr. Vincent Bérézowski (Inserm U1171), she developed two different cerebral in vitro models: A Read more…
We are very happy to be invited by our partner Molecular Devices at the user meeting of Taipei (Taiwan) and Beijing (China) this month to talk about phenotypic screening and 3D cell culture. We will be also in Japan to meet our local distributors and customers. On October 17, we Read more…
With more than 25 countries represented, NutrEvent is THE place to be for business and innovation in Food, Nutrition and Health. It will take place next week in Rennes congress centre (Couvent des Jacobins), on the 22nd and 22rd of October. Our stand will be on Eurasanté Pavilion (Level 1 Read more…
With more than 1100 researchers and exhibiting experts, “Rendez-vous Carnot” offers a complete ecosystem of R&D and innovation support. We will attend at two-day Rendez vous CARNOT (October 16-17 in Paris) to present our innovations on 3D cell culture with our unique and proprietary technology BIOMIMESYS®… Also we will present our activities Read more…
Last week we were glad to attend the kick-off meeting of MIMLIVEROnChip, funded by the french National Agency for Research (ANR). It was held in UTC Compiègne, and the project is coordinated by Pr Cecile Legallais (BIOMÉCANIQUE ET BIOINGÉNIERIE (BMBI Laboratory) – UMR CNRS 7338). This project aims at developing Read more…
It’s a large part of our work to reveal beauty (and secrets!) of cells in HCS Pharma thanks to different microscopy technologies. In this nice article, authors present the evolution of this field from first optical devices to most recent high-resolution technologies. It’s interesting to see that observation of cells Read more…
We are very happy to share with you about HCS and 3D in vitro models thanks to a labroots.com webinar on October 27, 2019! This webinar is made with our partner Molecular Devices and it will present you many tips on how to handle 3D cell culture systems such as Read more…
The annual congress of Biology and Health PhD students from Lille (André Verbert day) took place at the Faculty of Medicine Thursday, September 10th. During this day, PhD students, in third year of thesis, had to present their works by talks, flash-talks or posters. Our PhD student Véronique De Conto Read more…
Ask for high quality link by putting your email below We previously showed that human pluripotent stem cells (hiPSCs) provide a suitable model to study metabolic diseases upon hepatocyte-like cell (HLC) differentiation. In particular, HLCs have been used to model cholesterol metabolism regulation, by mimicking the main disease features in Read more…
In HCS Pharma, we have alreadytalked about Artificial Intelligence (AI) and the way it is useful in picture analysis. AI can obviously be used for many endeavours, like the shortening of drug discovery timeline as it is explained in the article “Deep learning enables rapid identification of potent DDR1 kinase Read more…
Last week we were glad to attend TERMIS-EU workshop in Nantes, dealing with 3D bioprinting in cancer research. There we presented 3 posters – that you can find on our website! – about BIOMIMESYS® product range, about iPSC-derived hepatocytes in BIOMIMESYS® Liver, and about BIOMIMESYS® for organ-on-chip systems… Moreover, we Read more…
We are very happy to be a part of the innovation landscape in France and to be supported (very efficiently) by BPI France. This year again we will be present at the big “Bpifrance Inno Génération” event in Paris, October 10. More than 10000 people will come to talk about Read more…
Ask for high quality link by putting your email below Objective: to develop a new liver-on-chip model that includes a relevant 3D matrix for hepatic cell growth and function with the use of of BIOMIMESYS® Liver hydroscaffold for a physiological 3D hepatocyte culture. View and download on Slideshare (low quality) Read more…
The extracellular matrix (ECM) is known as a molecular network of macromolecules present in all solid tissues (Figure 1), which plays an important role in the growth, migration and differentiation of cells. This ECM is part of a complex and plastic microenvironment in health and disease: its composition and physical Read more…
We were invited at the workshop organized by SMILL-E (Seeding Microsystems in Medecine in Lille – European-Japanese Technologies against Cancer) and Yncrea during MedFit event last week. This great workshop was about Digital and Micro systems for LifeTECH. Elodie was there to talk about innovative technologies for the screening of Read more…
Atopic dermatitis (AD) is a chronic, common inflammatory skin disease affecting 15-20% of children and 1-3% of adults worldwide. Loss of bacterial diversity from excess abundance of Staphylococcus aureus is associated with increased disease severity, nevertheless, how dysbiosis of the skin microbiome may influence atopic dermatitis pathophysiology is unknown. In Read more…
It was a great pleasure to be invited (thanks to our partner Molecular Devices) to present our work during these 2 events organized by selectBio in Rotterdam: Organoids and Tox Screening Europe 2019 on June 13-14 Organ-on-a-Chip and Tissue-on-a-Chip Europe 2019 on June 18-19 Both were of great interest for Read more…
Elodie, Véronique et Océane ont profité d’un moment très sympathique – et ensoleillé – lors du barbecue du parc Eurasanté ce midi… Merci à tous, et bon week-end 🙂
In the continuity of our scientific reviews about the important roles of Hyaluronic Acid (HA) in extracellular matrix (ECM) and cell behavior, we herein present this recent review describing the structure – function relationship of HA. As an important polysaccharide of ECM, HA plays an important role in cell and Read more…
Last week we were pleased to attend the founding congress of STCM (Société de Toxicologie Cellularie et Moléculaire), which was held in FIAP Jean Monnet (Paris). The topic was “Toxicology towards the 3rd dimension“. With a wide variety of talks from academic laboratories and from the industry, the content was Read more…
The founding congress of the french STCM (Société de Toxicologie Cellulaire et Moléculaire) will take place in Paris at the end of this week (13th-14th June, 2019). The theme of this meeting will be “Toxicology towards the 3rd dimension“. We are looking forward to attending this congress, and to becoming Read more…
We will be present this week and next week in Rotterdam, to talk about 3D cell culture and the importance of the microenvironnement in the relevance of in vitro models. As you known, to mimic human tissues, several parameters need to be taken into account: the target cells, nutrient intake Read more…
The extracellular matrix (ECM) is a three-dimensional macromolecular network composed of structural proteins (collagens, elastin), adhesion/signalling proteins (fibronectin, laminins), different proteoglycans, glycoproteins and glycosaminoglycans (GAGs). GAGs are structurally complex, but their structure is simply made up of repeating disaccharide building blocks composed of alternating uronic acid and hexosamine units. GAGs Read more…