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It is now well described that in tumor biopsies, the stiffness of the cancerous tissue is higher than the surrounding non-cancerous tissue of the same organ, with a described remodeling of the ECM. The increase in rigidity is related to the stimulation of fibroblasts that increase the synthesis of glycosaminoglycans, Read more…
Are you curious about confocal microscopy and the advantages of spinning disk? This article from Teledyne Imaging explains the technology with really simple words. You will understand why we have chosen this way to create high-quality 3D pictures. Our two “ImageXpress Micro Confocal” from Molecular Devices are perfect for our Read more…
It will a short article today to wish you a wonderful Christmas and all our best wish for this new year! We don’t known how will be 2020 but we are optimistic : We will work to cure complex diseases like cancers, we will explore new food production for a Read more…
Biomimesys is providing a great opportunity to culture human induced pluripotent stem cells (hiPSCs) in 3D and differentiate them into different kind of cell types including liver cells. Showcased by Méryl Roudaut at the 20th International Congress on In Vitro Toxicology (ESTIV2018), our co-development with the institute du thorax (U1087) Read more…
Ask for high quality link by putting your email below We previously showed that human pluripotent stem cells (hiPSCs) provide a suitable model to study metabolic diseases upon hepatocyte-like cell (HLC) differentiation. In particular, HLCs have been used to model cholesterol metabolism regulation, by mimicking the main disease features in Read more…
Stroke is the second leading cause of death worldwide and the most common cause of disability in adults. Ischemic stroke represents 80% of the cases. They cause oxygen and glucose deficit in the brain, leading to necrosis, edema formation, inflammation and apoptosis. Endogenous repair mechanisms, like cerebral plasticity, limit ischemia-linked Read more…
Nathalie and Elodie were in Marseille last week for BioFit event, where we had a booth under Clubster NHL (Nutrition-Health-Longevity) Pavilion: We would like to thank all the participants and collaborators who came to see us… We really enjoyed spending these 2 days with our neighbours from InEye-Pharma and ImmuneInsight: Read more…
Last week, it was a great pleasure to meet our partners during the kick-off meeting of ScaLABle-MEAT project, funded by EUREKA and the national funding agencies associated with the Eurostars program. It was held in the offices of Meatable (Delft). This ScaLaBlle-MEAT project is coordinated by Daan Luining (CTO and cofounder Read more…
Nathalie and Elodie will be present in Marseille for BioFit event next week! Indeed, HCS Pharma has a booth in Clubster NSL’s pavilion (number I20). Just stop by 🙂 It will be a pleasure to talk to you about the innovative 3D cell culture matrix BIOMIMESYS® and our related services Read more…
If you work in 3D cell culture, you should know our innovative technology BIOMIMESYS® just recognized as a Deep Tech Pionner by Hello Tomorrow. We have more and more practical examples of uses by our customers and we want to help them to be more efficient in the “everyday labo Read more…
Among more than 5,000 applicants from 128 different countries, HCS Pharma has been selected by Hello Tomorrow as one of “Deep Tech Pioneers” from their annual Global Challenge 2020 with our groundbreaking technology BIOMIMESYS®! BIOMIMESYS® is an unique groundbreaking 3D technology that associated the behavior of solid scaffold, by using Read more…
In 2019, Océane obtained her Master’s degree student in biotechnology specializing in production, purification and characterization of biomolecules at the ENSTBB (Bordeaux). After a three-month internship at IDEA Lab in vitro and a five-month internship at Fluofarma where she developed different in vitro efficiency tests for cosmetics industry, she worked Read more…
We were in Taiwan few weeks ago, invited by our partner Molecular Devices to talk about our skills in 3D cell culture, with our unique groundbreaking technology BIOMIMESYS® and our services for in vitro screening from cell assay development to picture and data analysis. It was also a perfect opportunity Read more…
The 2nd congress of Centers of Excellence in Neurodegeneration (CoEN) took place in Lille on the 14th and 15th of November 2019. It was organized by the Lille Center of Excellence for Neurodegenerative Disorders (LICEND). This meeting welcomed seven French research centers of excellence in neurodegenerative diseases: Lille (LICEND), CoEN Read more…
James W. Fawcett published the review « The extracellular matrix in plasticity and regeneration after CNS injury and neurodegenerative disease » in 2015, highlighting the key role of the chondroitin sulfate proteoglycans (CSPGs) of the extracellular matrix (ECM) in brain plasticity. CSPGs are present in the brain extracellular matrix and Read more…
Last week, our study director Elodie was in Rennes to participate in NutrEvent! We had a booth there, under NSL Clubster pavilion (Lille Northern France Health and Nutrition clubster). It was a pleasure for her to present our activities in imaging and our 3D cell culture products to the visitors! Read more…
Elodie is waiting for you on the first floor at Nutr’event 2019! HCS Pharma stand is n° D6/2, on Clubster NHL pavilion. She will be glad to discuss with you about: our in vitro tests for the objectivation of your claims on human cells (e.g. nutraceutical, dermocosmetic claims) our innovative Read more…
Since last year, our PhD student Véronique De Conto has been working on the impact of microenvironment in cerebral in vitro model. On the supervision of our study director Dr. Elodie Vandenhaute and her thesis director Pr. Vincent Bérézowski (Inserm U1171), she developed two different cerebral in vitro models: A Read more…
We are very happy to be invited by our partner Molecular Devices at the user meeting of Taipei (Taiwan) and Beijing (China) this month to talk about phenotypic screening and 3D cell culture. We will be also in Japan to meet our local distributors and customers. On October 17, we Read more…
With more than 25 countries represented, NutrEvent is THE place to be for business and innovation in Food, Nutrition and Health. It will take place next week in Rennes congress centre (Couvent des Jacobins), on the 22nd and 22rd of October. Our stand will be on Eurasanté Pavilion (Level 1 Read more…
With more than 1100 researchers and exhibiting experts, “Rendez-vous Carnot” offers a complete ecosystem of R&D and innovation support. We will attend at two-day Rendez vous CARNOT (October 16-17 in Paris) to present our innovations on 3D cell culture with our unique and proprietary technology BIOMIMESYS®… Also we will present our activities Read more…
Last week we were glad to attend the kick-off meeting of MIMLIVEROnChip, funded by the french National Agency for Research (ANR). It was held in UTC Compiègne, and the project is coordinated by Pr Cecile Legallais (BIOMÉCANIQUE ET BIOINGÉNIERIE (BMBI Laboratory) – UMR CNRS 7338). This project aims at developing Read more…
It’s a large part of our work to reveal beauty (and secrets!) of cells in HCS Pharma thanks to different microscopy technologies. In this nice article, authors present the evolution of this field from first optical devices to most recent high-resolution technologies. It’s interesting to see that observation of cells Read more…