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Many skin diseases, including psoriasis and basal cell carcinoma, are associated with microbial dysbiosis characterized by reduced C. acnes prevalence. C. acnes is a facultative anaerobic bacterium that is frequently found on the human skin. This bacterium is both an opportunistic pathogen and a commensal organism. Indeed, most individuals are Read more…
The California Cruelty-Free Cosmetics Act, SB 1249, was introduced in the California State Legislature. On Jan. 1st, 2020 the bill will prohibit the sale of animal-tested cosmetics in the state. The European Union ended importation and sale of any new cosmetics that have been tested on animals in 2013 with Read more…
Since 2 years, we saw AI (Artificial Intelligence) spreading in more and more domains, sometime presented as the “panacée” of all problems. In healthcare, and especially in drug discovery, many announces are done but, to be honest, very few results are published. In the article, the author explains the advantages Read more…
The annual SCMC congress (Société Cerveau et Maladies Cérébrovasculaires – Brain and Cerebrovascular diseases Society) took place in Lille last week, in the Faculty of Medecine. The congress was organized in three sessions. The first session was about cerebrovascular development and maturation. The conferences began with a lecture about blood-brain Read more…
Wound healing is a crucial physiological process rehabilitating the unity of the skin barrier. Inflammation in wound healing is a weapon with two edges. It is indispensable but must be strongly regulated both temporally and spatially. In this recent study, Li et al. show skin commensal S. epidermidis produces a Read more…
Last week HCS Pharma team enjoyed Forum Labo Paris! We enjoyed it twofold because : we won our booth on the Lab’StartUp Village, in the heart of the fair. It gave us the opportunity to present our BIOMIMESYS® products! we won a price for our amazing photo of liver cells… Read more…
We will be happy to meet you at In-cosmetics Global at Porte de Versailles this week from 2nd-4th of April (https://www.in-cosmetics.com/global/) and to present you our multiplex offer (based on in vitro automated cell Imaging) that permit to evaluate simultaneously one active ingredient or raw extract for different marketing claims Read more…
Our CEO, Nathalie, has presented company strategy in front of many investors at Start West event in Rennes. She explained especially why our next fund rising is mandatory to develop internationally our exclusive BIOMIMESYS® products. She also shared with attendees her vision of the necessity of 3D cell culture to Read more…
Véronique De Conto, doctorante chez HCS Pharma, présentera ce jeudi 28 mars à Lille, au congrès annuel de la Société Cerveau et Maladies Cérébrovasculaires, le développement d’un modèle cérébral en 3 dimensions incluant le microenvironnement matriciel pour la recherche de nouveaux médicaments contre la maladie de Parkinson. Introduction : 90% Read more…
The skin is inhabited by Bacteria, archaea, fungi and viruses, collectively referred to as the skin microbiota. These commensals serve as first line of defense at the skin surface and play a vital role in both the establishment and maintenance of the skin’s immune system. Among the bacteria, some of Read more…
Next week HCS Pharma will be present both at Forum Labo Paris (26th-28th March ) and at SCMC congress in Lille (28-29th March)! In Forum Labo we will have our own stand in the Lab’StartUp Village (stand G11), thanks to the organizers for selecting BIOMIMESYS® Brain for the fair! We Read more…
Victoria has joined us for a six-month internship in collaboration with the University of Technology of Compiègne. She will develop a liver biochip, using the BIOMIMESYS® Liver hydroscaffold. Victoria obtained her bachelor’s degree in Cellular Biology and Physiology. Currently she is finishing the 2nd year of Master’s Degree in Biotechnologies Read more…
Skin commensals are crucial in the maintenance of the epithelial barrier function, regulation of the host immune system, and prevent invasion of other pathogenic microbes. In this article, published in September 2018, Burmeister et al show that Staphlylococcus, Streptococcus, Pseudomonas, Corynebacterium, and anaerobes have both beneficial and harmful effects depending Read more…
The neurovasculaire unit (NVU) is composed of brain microvascular endothelial cells (BMECs) that form the Blood-Brain-Barrier (BBB), pericytes, neurons and glial cells. It regulates substance transport between blood and brain. BBB and NVU dysfonctions are associated with numerous neurological pathologies. Animal models are traditionally used in medical research but the Read more…
The first version of BIOMIMESYS Brain allows to form neurospheres. We now developped a new version of BIOMIMESYS Brain, which allows to form neuronal networks. This version have a higher porosity than BIOMIMESYS Brain (Neurosphere), that allows to better disperse the cells and thus to form cell network instead of Read more…
After a bachelor of science in biology, Solenne has been graduated with a two-year diploma “DUT Génie Biologique”, specialized in biological and biochemistry analysis. Afterwards, she wenty on with a professional bachelor’s degree dealing with the development of cosmetic and health products at Université Bretagne Sud in Vannes, where she Read more…
Jean-Baptise obtained his Master’s degree in Cellular and Molecular Biology at Paris-Sorbonne University in 2018 after a six-month internship with us. He focused on the development of a human microbiota model in collaboration with the Pharmacology Lab of University of Rennes 1 (INSERM U1230). He will keep on working on Read more…
Our CEO, Nathalie is the Chairwoman of the session “ Next Generation High-Content Bioimaging – Phenotypic Discovery” (Track 3 – session 2) at next SLAS Barcelona event. This event will bring together more than 1,000 scientists and technologists from around the world. The theme for the 2019 Europe Conference is Read more…
BIOMIMESYS® Oncology is mostly composed of hyaluronic acid (HA), biofunctionnalized with undenaturated collagen I. HA, by interacting with its binding proteins (CD44, RHAMM, ICAM-1), is an active participant in inflammatory, angiogenic, fibrotic and cancer-promoting processes (Figure 1). We are currently looking at the effect of different elastic moduli of BIOMIMESYS® Read more…
We were really happy to participate in SLAS2019 in Washington last week. In addition to spending a few relaxing days in Washington, we enjoyed the warm welcome of the US team of Molecular Devices. We had the opportunity to present HAPIx, our HCS robotic platform fully designed and integrated by Read more…
HCS Pharma is one of the winner of the Lab’StartUp village, organized by Forum Labo! As such, we have won a stand in the heart of the forum (March 26-28, 2019)… Thanks a lot to the committee for evaluating our application to this prize, and for selecting our new product Read more…
Extracellular matrix (ECM) is known to have an influence on physiological processes and on tumour progression: ECM properties (composition, stiffness) modulate cell proliferation, migration, invasion and epithelial-to-mesenchymal transition (EMT). For example, EMT is inhibited by laminin-rich environment whereas it is promoted in fibronectin-rich ECM (Chen et al 2013. Differentiation 86, Read more…
Most potential drug candidates (90%) fail within the clinical trials, mainly because of lack of efficacy. What if the pharmaceutical industry uses predictive human in vitro models in early drug discovery ? View and download on Slideshare (low quality) https://fr.slideshare.net/hcspharma/a-groundbreaking-3d-cell-culture-technology-for-hcs-biomimesys-hydroscaffold Ask for high quality link by putting your email below