The ExtraCellular Matrix: a focus on GlycosAminoGlycans and Hyaluronan

The extracellular matrix (ECM) is a three-dimensional macromolecular network composed of structural proteins (collagens, elastin), adhesion/signalling proteins (fibronectin, laminins), different proteoglycans, glycoproteins and glycosaminoglycans (GAGs). GAGs are structurally complex, but their structure is simply made up of repeating disaccharide building blocks composed of alternating uronic acid and hexosamine units. GAGs Read more…

Skin microbiota protects their host from oxidative stress through secreted antioxidant RoxP

Many skin diseases, including psoriasis and basal cell carcinoma, are associated with microbial dysbiosis characterized by reduced C. acnes prevalence. C. acnes is a facultative anaerobic bacterium that is frequently found on the human skin. This bacterium is both an opportunistic pathogen and a commensal organism. Indeed, most individuals are Read more…

Feedback from SCMC congress: Maturation and Development of Cerebrovascular System

The annual SCMC congress (Société Cerveau et Maladies Cérébrovasculaires – Brain and Cerebrovascular diseases Society) took place in Lille last week, in the Faculty of Medecine. The congress was organized in three sessions. The first session was about cerebrovascular development and maturation. The conferences began with a lecture about blood-brain Read more…