We are delighted to announce that a very interesting study using BIOMIMESYS® to study the metastasis of breast cancer has been published in Experimental Hematology & Oncology Journal (Impact factor 11,4). This article untitled “ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells” (Cicero, Read more…
November was the smoked-free month, and we hope that it was successful for you!* Indeed, smoking is the first cause of lung cancer, which is the 3th most common cancer and the first leading cause of cancer-related mortality in France, according to The French National Cancer Institute. Worldwide, it is Read more…
HCS Pharma announces the closure of the “MIMLIVERonChip” project, funded by the French National Research Agency (ANR, project ANR 19 CE19-0020) and coordinated by BMBI Biomechanics and Bioengineering joint research unit (UTC/ CNRS), headed by Dr Cécile Legallais, CNRS research director. This project led to the publication of Taha Messelmani’s Read more…
Yesterday Julien Cicero defended his PhD thesis in OncoLille Institute, about the role of neurotrophins and related receptors in brain metastasis of triple negative breast cancer. What a great thesis defense, we enjoyed a lot his very clear presentation and his responses to the questions of the committee. Perfect time Read more…
ELRIG Drug Discovery 2023 congress will take place in Liverpool next week (October, 18 & 19th 2023). Our project leader Dr. Véronique De Conto will have the pleasure for presenting a poster about High Content Screening in 3D models including the tumoral Extracellular Matrix. Abstract: In oncology, 97% of drug Read more…
This is the end of Rania‘s 6-month internship in HCS Pharma about a new liver biochip system. After a first publication “Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix” in collaboration with the University of Technology of Compiègne (UTC) using the BIOMIMESYS® Liver hydroscaffold™ and HepG2/C3A (hepatocellular Read more…
Thomas Meynard is a PhD student in OncoLille Laboratory (Canther Lab, Mucine Team), under the supervision of Dr. Isabelle Van Seuningen and Dr. Vincent Senez. His PhD work is focused on the development of microfluidic systems to study Pancreatic Ductal AdenoCarcinoma (PDAC). To reproduce the tumoral Extracellular Matrix (ECM), he Read more…
Julien Cicero, with whom we are collaborating about the study of breast cancer metastasis mechanisms, was proud to present his PhD work during the last EACR conference. It was held in Torino (Italy) last month, during which Julien could discuss with cancer researchers from all around the world. His poster Read more…
Chez HCS Pharma, nous sommes ravis de partager avec vous les avancées significatives que nous avons réalisées dans nos projets de recherche et développement. Avant de commencer, nous tenons à remercier “La Gazette du Laboratoire” pour leur soutien continu et leur couverture détaillée de nos efforts. Notre entreprise, basée à Read more…
Last week, we had the pleasure to participate in the conference about Alternatives to Animal Experimentation which was held last week in Biocitech park, Romainville, France. It was organized by Adebiotech think tank, and gathered researchers from private companies and academia, and also people from organizations like FC3R and PETA Read more…
Metastasis is the leading cause of death in many cancers. Metastases are particularly harmful when they affect vital organs such as the brain or liver, severely compromising the patient’s quality of life and leading to death. The difficulties of studying metastases in animal models (time, cost, ethical issues) have meant Read more…
In recent years, 3D cell culture has emerged as a promising approach to studying the immune system and its interactions with cancer cells. Indeed, 3D cell culture mimics better the natural architecture of tissues and provides a more physiologically relevant models for drug discovery. One of the major advantages of Read more…
A driver oncogene is a gene that, when activated by mutation or altered in expression, contributes importantly to the development and progression of cancer. In other words, alteration of this kind of genes lead to the transformation of a normal cell into a cancerous cell by activating signaling pathways involved Read more…
The event “Research and Innovation 2023 – Accelerating future DD” of The European Laboratory Research and Innovation Group (ELRIG) took place in Cambridge on March 29th and 30th 2023. Our project leader Dr. Veronique De Conto attended this event with our academic partner Dr.Marie Fernandes (CNRS, Oncolille, Canther Lab), who Read more…
HCS Pharma is very pleased to participate to “Building Biology in 3D” symposium of the Society for Laboratory Automation and Screening (SLAS), in Cambridge, United Kingdom 20-21 April 2023. Veronique De Conto, our project leader in in vitro pharmacology will present two digital posters about the use of BIOMIMESYS® hydroscaffold, Read more…
Organoids are three-dimensional structures made of cells, which can be derived from stem cells to mimic the structure and function of real organs. They are useful tools for studying human development, disease modeling, drug screening, and personalized medicine. Recent advancements in organoid research have focused on improving their complexity and Read more…
Why is testing important? One million cases of colon cancer are diagnosed each year around the world. Colorectal cancer develops slowly. The tumor, called polyp, appears on the inner wall of the colon and rectum. The evolution of a polyp into cancer can last about ten years. The test can Read more…
The beginning of 2023 is tremendous for HCS Pharma in terms of new oncology-related collaborative R&D projects, with three of them accepted and granted by ANR (Agence Nationale pour la Recherche) through the Plan France Relance, and by the Région Hauts-de-France through STIMuLE plan. It has been announced in a Read more…
The Brain Week is an international event organized simultaneously in about 100 countries and more than 120 cities in France. Its aim is to raise public awareness of the importance of brain research. It is an opportunity for many researchers to meet the public and share with them the advances Read more…
After a first publication “Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix” in collaboration with the University of Technology of Compiègne (UTC) using the BIOMIMESYS® Liver hydroscaffold™ and HepG2/C3A (hepatocellular carcinoma cell line) in Biochip, the project continue with Rania Chibani, who has joined us for a Read more…
2.2 million cases of breast cancer were identified in 2020 by the WHO. This cancer is the first cause of cancer in women. It develops in the glandular lobes or milk ducts. Five subtypes of breast cancer have been defined but their origin is not yet determined. The heterogeneity of Read more…
