Because BIOMIMESYS® is made with the heart, he can also love !

Histological sections of liver organoids (left) and BIOMIMESYS® (not) alone (right)

BIOMIMESYS® matrix produced by HCS Pharma is a unique groundbreaking 3D cell culture technology which associates both the properties of a solid scaffold (porosity and structure maintenance) and the properties of a hydrogel (cell-matrix interaction). BIOMIMESYS® matrix are made of Hyaluronic Acid (HA), the main glycosaminoglycan (GAG) of the ECM, collagens and adhesion proteins. Its composition and stiffness can be adapted to each organ, in health and disease. That allows to provide a physiological cell culture microenvironment reproducing all aspects of human tissues, including matrix architecture, cellular organization, cell-cell and cell-matrix interactions.

Moreover, HCS Pharma is also specialized in phenotypic screening, to analyzed toxic or therapeutic effects of molecules by automated confocal microscopy and image analysis. Phenotypic screening allows to take into account all complex mechanisms and pathways involved in multifactorial diseases, like cancers or neurodegenerative diseases.

Taken together, 3D cell culture in BIOMIMESYS® and phenotypic screening can really improve the selection of drug candidates in preclinical trials, for a better success rate in clinical trials.

Feel free to contact us if you want more information about BIOMIMESYS® matrix provided in ready-to used multiwell plates, or about our services in pharmacological assessments in 3D by cellular imaging!



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