In this presentation, Nathalie MAUBON (CEO HCS Pharma), give an overview of drugs discovery, from pre-19th century are, where trials are done on humans, to nowadays where clinical trials are safer but with a dramatic rate of failure. She explains what are the “target base screening” and the “phenotypic screening in 2D” in pharmaceutical industries, why they are irrelevant to find drugs against complex deceases, and very inefficient to build the healthcare with the next 50 years.
Nathalie shows the importance to consider not only cells in drugs discovery but also the whole organ (cells, extracellular matrix, communication with other organs) to prepare the next step of personalized and regenerative medicine.
This discussion is illustrated by concrete examples realized with BIOMIMESYS® by HCS Pharma and partners.
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