BIOMIMESYS® Liver recreates the complex cellular microenvironment of the liver to extend longevity and functionality of hepatocytes in culture:

  • The life of human primary hepatocytes grown in a 2D sandwich is low, 3-10 days (1) and is accompanied by dedifferentiation, leading to the loss of their functions.
  • In 2D culture, HepG2 due their ability to proliferate quickly, reach confluence and have low hepatocyte functions limiting their use for metabolic studies or drug induced liver injury, DILI (2)

Therefore, a culture in BIOMIMESYS® Liver:

  • Doubles the human primary hepatocytes viability compared to a 2D culture.
  • Allows HepG2 to grow without impairing the viability and morphology for at least 4 weeks.

Grégory MAUBON

Grégory MAUBON is Chief Data Officer and digital coordinator at HCS Pharma, a biotech startup focused in high content screening and complex diseases. He manages IT missions and leads digital usages linked to company needs. He is also a Augmented Reality Evangelist (presenter and lecturer) since 2008, where he created and founded in 2010 RA'pro (the augmented reality promotion association). He helped many companies (in several domains) to define precisely their augmented reality needs and supported them in the implementation.


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