The morphological changes in cells during differentiation are accompanied by a profound change at the molecular level. In vivo, the adipocyte differentiation process includes early and late events due to differential gene regulation. The appearance of these markers is a sign of differentiation of pre-adipocytes and hence the development of adipose tissue.
Genetic markers such as C/EBPα (1) and PPARγ2 (2) are used to assess the complete differentiation of preadipocytes.
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