Skin is a major target of oxidative stress. Free radicals are unstable chemical species, highly reactive, being formed by cellular entities. Increased production of these species without proper effective action of endogenous and exogenous antioxidant systems generates a condition of oxidative stress and participates in skin aging process and skin disorders apparition. HCS Pharma has developed tests to assess actives efficacy against it.
In vitro ROS assessment : does my active reduce cellular ROS production ?
Reactive Oxygen Species (ROS) represent the major agents of oxidative stress and induce pathologies by damaging lipids, proteins, and DNA.
In vitro gluthatione stock assessment : does my active restore gluthatione stock ?
Glutathione (GSH) is implicated as an important antioxidant in the skin’s defense against the accumulation of ROS. Endogenous GSH pool reduction is a cause of oxidative stress damages associated with mitochondrial deterioration.
In vitro lipid peroxidation assessment : does my active reduce lipid peroxidation ?
Lipid peroxidation represents the oxidative degradation process of lipids, including membrane lipids. This process is initiated by free radical species transfering electrons from the lipids chain, and creating cell damages by producing lipid radicals.
