Visible pigmentation of the skin and hair depends primarily on the functions of melanocytes, a very minor population of cells specialized in the synthesis and the distribution of the pigmented biopolymer melanin.
Melanocytes Pigmentation Assessment : Monolayer of melanocytes
Pigmentation is particularly regulated at the cellular level by melanocytes synthesizing melanin within melanosomes, which can be produced in varying sizes, numbers, and densities. In order to evaluate the effects of your actives on this synthesis, HCS Pharma offers you a melanocytes pigmentation test using a model of monolayer of melanocytes.
Skin Pigmentation Assessment : RHPE
Pigmentation properties of your ingredients can also be evaluated on a Reconstructed Human Pigmented Epidermis (RHPE). This model allows to study the transfer of melanin from melanocytes to neighboring keratinocytes, which is tightly linked to skin pigmentation too.