Lipid peroxidation is the oxidative degradation of lipids. Reactive oxygen species are the major initiators of lipid peroxidation: membrane-bound polyunsaturated fatty acids (like arachidonic and linoleic acids) are their major targets. The byproducts of lipid peroxidation cause direct damage to cell membranes. They also form protein adducts resulting in cell and tissue damage. Lipid peroxidation is involved in many human diseases, including diabetes and cardiovascular disease.
Pre-exposition to compounds is used to assess their potential preventive effects. You can also co-expose your compounds to study acute protective effects. Using image analysis, we can assess the anti-oxidative effects of your compounds compared to Vitamine E.
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