To add the extracellular matrix in your 3D cell assays
We provide services on BIOMIMESYS® technology
Save your time and ask for our custom services on BIOMIMESYS®! We can also setup your experiments for a technology transfer to your laboratory if needed. You can choose between our different BIOMIMESYS® hydroscaffold (or define your hydroscaffold), cells, and endpoints !
If you want to know more about BIOMIMESYS®, contact us!
We also continue R&D to set-up our own 3D cellular assays
We continue our assay development in 3D culture on BIOMIMESYS® technology. First of all, We are going to transfer all already developed 2D assays in 3D. Furthermore, we continue other assay development for screening on different therapeutic areas.
We work with our partners and others on :
– metabolic disease : as NAFLD, NASH, fibrotic liver
In addition to just growing the cells in a medium rich in fatty acid or glucose, we also develop 3D culture models whose cellular microenvironment is modified as observed in the pathology to obtain models closer to the pathophysiology.
– (immuno)oncology : with modification of the composition of BIOMIMESYS® hydroscaffold by increasing the concentration of HA and collagen 1, we modify the microenvironnement of cancer cells grown in this hydroscaffold.
Using this 3D cellular models of oncology including ECM for screening, we will be able to found compounds to target ECM in addition to killing cancer cells.
– neurodegenerative disease : First results on neuronal cells in 3D BIOMIMESYS® hydroscaffold show interesting results with neurites between cells.
We have done also our first 384-well plates allowing us to perform phenotypic screening in this plate format :
If you are interested to participate to one of this R&D programs and to be the first to do a phenotypic 3D screening in this system, do not hesitate to contact us!