Have you missed our last webinar with Molecular Devices about 3D oncology models? In April, our project leader Elodie was talking about how to establish and image physiologically relevant 3D cancer in vitro models, using BIOMIMESYS Oncology as a surrogate for the tumoral extracellular matrix. Our product BIOMIMESYS® Oncology matrix Read more…
Please feel free to follow us in these conferences: on Thursday 27th, we will attend the virtual Joint Meeting of the French and German Societies for Matrix Biology. Let’s talk about BIOMIMESYS technology (poster n°105, poster session 2) and BIOMIMESYS Adipose Tissue in particular (poster n°97, poster session 1)! You Read more…
We are very happy to invite you to our next webinar about 3D cellular cancer models and our BIOMIMESYS® Oncology matrix which allows cancer cells to be cultured in a tumor-like environment, with the possibility to tune the composition and stiffness of the matrix. We will also share our best Read more…
3D cell culture systems have recently emerged as promising tools for reproducing the cellular environment and the organization of tissues/organs, where cells are connected to each other and to the surrounding extracellular matrix (ECM). In this presentation we will focus on BIOMIMESYS® Liver and will discuss about its different applications. Read more…
Cultivated meat is meat produced from cells cultures, and it appears as a promising alternative to traditional meat derived from animals. Sometimes known as clean meat, cultured meat or in vitro meat, such cells are cultured in a customizable and controlled platform. The manipulation, enhancement as well as adaptation of Read more…
When Tuesday, March 23, 2021 – 1PM (CET) / 8PM (CST) / 9PM (JST) / 7AM (EST) Thursday, March 25, 2021 – 9AM (CET) / 4PM (CST) / 5PM (JST) / 3AM (EST) Where Online, using zoom.us and live on Youtube What 3D cell culture systems have recently emerged as promising tools Read more…
We are glad to share with you confocal microscopy pictures showing the interactions between two proteins (complexes are the red spots) at the surface of breast cancer cells (MDA-MB-231) cultivated in 3D in BIOMIMESYS matrix. This was made possible by using proximity ligation assay (PLA). The cell nuclei are in Read more…
When Tuesday, February 23, 2021 – 1PM (CET) / 8PM (CST) / 9PM (JST) / 7AM (EST) Thursday, February 25, 2021 – 9AM (CET) / 4PM (CST) / 5PM (JST) / 3AM (EST) Where Online, using zoom.us and live on Youtube What 3D cell culture systems have recently as promising Read more…
Context It is well established that the extracellular matrix (ECM) plays a central role in cell homeostasis and cell adhesion by providing support, promoting cell-to-cell communication and differentiation (or dedifferentiation and tumoral progression when the ECM is modified). The composition but also the stiffness and elasticity of the ECM have important Read more…
As you may now, in HCS Pharma we strongly believe that the critical point of the human health evolution in next years is the in vitro 3D cell culture, especially for complex diseases like cancer [1]. It’s why we work hard on our exclusive BIOMIMESYS® technology. As experts in HCS and cell imaging, we must master all the process : 3D biological models, 3D cell culture, volumetric pictures acquisition, 3D reconstruction and segmentation of cells and ECM compounds, 3D parameters extraction and, of course, biological interpretations. As explained in our VisuAI R&D project, the 3D reconstruction and segmentation step is not simple.
Clinicians and researchers worldwide are actively studying the mechanisms governing the infection of humans by SARS-CoV-2 and its consequences on their health, with the objective is to find effective therapies. We all aknowledge their important role in the current crisis – and in preventing future ones! While respiratory symptoms are Read more…
HCS-Pharma is pleased to launch BIOMIMESYS® Liver and Oncology in ready-to-use 384-well plate format for screening applications. Adopt BIOMIMESYS® 3D cell culture systems and obtain more predictive in vitro models. You can find our presentations in PDF format for BIOMIMESYS® Liver for BIOMIMESYS® Oncology For more information, contact us at hello@biomimesys.com
Parkinson’s disease affects more than 6 million people worldwide. This neurodegenerative disease is characterized by the death of dopaminergic neurons in the substantia nigra pars compacta, with intracellular accumulation of alpha-synuclein aggregates known as Lewi bodies. This neuronal loss leads to a decrease in the neurotransmitter dopamine that cause mainly Read more…
On the occasion of the breast cancer awareness month, HCS Pharma is willing to thank all researchers working in the field to better understand the pathophysiology of disease, with the objective to find more efficient anti-cancer therapies. We would like to warmly thank the researchers with whom we are collaborating Read more…
Vaihere Cheung obtained her technology A-level (STL) in 2018 at La Mennais, in French Polynesia. Then she came to metropolitan France to reach a technician diploma in Biological engineering, specialized in biological and biochemical analysis, at the University of Lyon. During her studies, Vaihere did an internship in HCS Pharma Read more…
At the occasion of the Breast Cancer Awareness Month, we would like to highlight the role of the interplay between the extracellular environment and the Cancer-Associated Fibroblasts (CAFs) on the tumoral development, including breast cancers. In our previous articles, we described the pro-tumoral effect of the extracellular environment. Moreover, an Read more…
This summer, Vitali et al. published an article in the Open Access Journal Cancers in which they assessed anticancer combination to treat neuroendocrine tumors (NETs) using in vitro models (2D + 3D cultures in BIOMIMESYS hydroscaffolds). A NET arises in the specialized cells of the neuroendocrine system, which have traits of Read more…
You may have noticed on our website: we have changed our logo this summer, and it is the most visible part of our strategic development. Of course, we are always experts in HCS and cell imaging but, for us, it is the perfect time to show our deep expertise in Read more…
In the continuity of our scientific reviews about the important roles of Hyaluronic Acid (HA) in extracellular matrix (ECM) and cell behavior, we herein present this recent review describing the structure – function relationship of HA. As an important polysaccharide of ECM, HA plays an important role in cell and Read more…
As we are involved in some very interesting projects, we have the chance to work with amazing specialists in many field. All these people help us to make the BIOMIMESYS® technology better, easier to use and well adapted to their work. We asked them to explain why they use BIOMIMESYS® Read more…
Abstract The ATP Binding Cassette transporter B1 (ABCB1) induces chemoresistance in osteosarcoma, because it effluxes doxorubicin, reducing the intracellular accumulation, toxicity, and immunogenic cell death induced by the drug. The ATP Binding Cassette transporter A1 (ABCA1) effluxes isopentenyl pyrophosphate (IPP), a strong activator of anti-tumor Vγ9Vδ2 T-cells. Recruiting this population Read more…
As many companies in France and in the world, the COVID-19 pandemic deeply affects our activities. For safety reasons, most of our work is now done remotely but we maintain essential activity in laboratories to take care of our cells and try to finish our ongoing customer studies. The situation Read more…
We will give a presentation next week (on Tuesday, 10th of March 2020) at the High-Content Cellular Imaging User meeting organized by our partner Molecular Devices, which will take place in Leiden (Netherlands). It is a great pleasure for us to attend the meeting, and to talk about the applications, Read more…