Last week HCS Pharma team enjoyed Forum Labo Paris! We enjoyed it twofold because : we won our booth on the Lab’StartUp Village, in the heart of the fair. It gave us the opportunity to present our BIOMIMESYS® products! we won a price for our amazing photo of liver cells… Read more…
HCS Pharma is one of the winner of the Lab’StartUp village, organized by Forum Labo! As such, we have won a stand in the heart of the forum (March 26-28, 2019)… Thanks a lot to the committee for evaluating our application to this prize, and for selecting our new product Read more…
Most potential drug candidates (90%) fail within the clinical trials, mainly because of lack of efficacy. What if the pharmaceutical industry uses predictive human in vitro models in early drug discovery ? View and download on Slideshare (low quality) https://fr.slideshare.net/hcspharma/a-groundbreaking-3d-cell-culture-technology-for-hcs-biomimesys-hydroscaffold Ask for high quality link by putting your email below
We will be at the next edition of SLAS meeting in Washington, DC February 2nd and 3th. If you wish to meet us, we will welcome you on our partner’s booth, Molecular Devices (#437) We will talk about “Phenotypic screening in 3D culture including ECM: advantages and challenges” on Monday, Read more…
Many categories of drugs can induce hepatotoxicity, so improving the prediction of toxic drugs is important. In vitro models using human hepatocytes are more accurate than in vivo animal models. Good in vitro models require an abundance of metabolic enzyme activities and normal cellular polarity. However, none of the in Read more…
Cells have diverse circuitry to sense and respond to extrinsic metabolic signals. Extracellular matrix (ECM) reorganization which is central to both tissue expansion and regeneration. ECM remodeling is also a signature of pathological processes, such as tumorigenesis. In this study from Sullivan et al., they show that increased migration in Read more…
“Regulation needs to catch up with innovation.” Henry Paulson – CEO Goldman Sachs A very nice state of art about animal testing and its alternatives can be found in the new article “Animal Testing and its Alternatives – the Most Important Omics is Economics” from Hartung et al. This study established that Read more…
We had the pleasure to attend ELRIG Fr meeting in Bischoffsheim (near Strasbourg) on the 23-24th of May. There we enjoyed meeting our partners Molecular Devices and Integra biosciences, and seeing great presentations about the last trends in automation. Our collaborator Karim Si-Tayeb presented his amazing results regarding the differentiation Read more…
Interesting paper from Christian Dani team about the potential of Brown and brown-like adipocytes (BAs) proginitors derived from hiPSCs to dissipate energy stored and the promising potential to treat obesity and metabolic disorder. In this publication, they describe the capacity of human-induced pluripotent stem cells (hiPSCs) to generate BAPs able Read more…
Our new poster on BIOMIMESYS® technology is now avalaible on this link. It presents the use of this scaffold on our automated platform (Hapix), with the development of a 3D cell model for steatosis and phospholipidosis assessment as an example. Automated HepG2 cells seeding, medium renewal, spheroids treatment, fixation, staining and Read more…
The first EUROoC meeting, dealing with organ-on-chip research and organized by the Chemical and Biological Microsystems Society (CBMS), will take place on the 24th-25th of May 2018 in Stuttgart (Germany). Interestingly, this new workshop will address the engineering challenges related to the design, fabrication and implementation of organ-on-chips (OOC) and microphysiological systems. Among other Read more…
According to a report issued by the Tufts Center for the Study of Drug Development, the costs associated with bringing a novel drug to market exceed $2.5 billion per successful compound
#hcs by multiplexing assays on #3d cell culture have many advantages to find more efficient new drugs for #cancer treatment. Progress in the IT part, on softwares, on the uses on big data and in the machine on speed and sensitivity allow to do multiplexing assays in HCS . This article Read more…