When Tuesday, February 23, 2021 – 1PM (CET) / 8PM (CST) / 9PM (JST) / 7AM (EST) Thursday, February 25, 2021 – 9AM (CET) / 4PM (CST) / 5PM (JST) / 3AM (EST) Where Online, using zoom.us and live on Youtube What 3D cell culture systems have recently as promising Read more…
Context It is well established that the extracellular matrix (ECM) plays a central role in cell homeostasis and cell adhesion by providing support, promoting cell-to-cell communication and differentiation (or dedifferentiation and tumoral progression when the ECM is modified). The composition but also the stiffness and elasticity of the ECM have important Read more…
As you may now, in HCS Pharma we strongly believe that the critical point of the human health evolution in next years is the in vitro 3D cell culture, especially for complex diseases like cancer [1]. It’s why we work hard on our exclusive BIOMIMESYS® technology. As experts in HCS and cell imaging, we must master all the process : 3D biological models, 3D cell culture, volumetric pictures acquisition, 3D reconstruction and segmentation of cells and ECM compounds, 3D parameters extraction and, of course, biological interpretations. As explained in our VisuAI R&D project, the 3D reconstruction and segmentation step is not simple.
Clinicians and researchers worldwide are actively studying the mechanisms governing the infection of humans by SARS-CoV-2 and its consequences on their health, with the objective is to find effective therapies. We all aknowledge their important role in the current crisis – and in preventing future ones! While respiratory symptoms are Read more…
HCS-Pharma is pleased to launch BIOMIMESYS® Liver and Oncology in ready-to-use 384-well plate format for screening applications. Adopt BIOMIMESYS® 3D cell culture systems and obtain more predictive in vitro models. You can find our presentations in PDF format for BIOMIMESYS® Liver for BIOMIMESYS® Oncology For more information, contact us at hello@biomimesys.com
Parkinson’s disease affects more than 6 million people worldwide. This neurodegenerative disease is characterized by the death of dopaminergic neurons in the substantia nigra pars compacta, with intracellular accumulation of alpha-synuclein aggregates known as Lewi bodies. This neuronal loss leads to a decrease in the neurotransmitter dopamine that cause mainly Read more…
On the occasion of the breast cancer awareness month, HCS Pharma is willing to thank all researchers working in the field to better understand the pathophysiology of disease, with the objective to find more efficient anti-cancer therapies. We would like to warmly thank the researchers with whom we are collaborating Read more…
Vaihere Cheung obtained her technology A-level (STL) in 2018 at La Mennais, in French Polynesia. Then she came to metropolitan France to reach a technician diploma in Biological engineering, specialized in biological and biochemical analysis, at the University of Lyon. During her studies, Vaihere did an internship in HCS Pharma Read more…
At the occasion of the Breast Cancer Awareness Month, we would like to highlight the role of the interplay between the extracellular environment and the Cancer-Associated Fibroblasts (CAFs) on the tumoral development, including breast cancers. In our previous articles, we described the pro-tumoral effect of the extracellular environment. Moreover, an Read more…
This summer, Vitali et al. published an article in the Open Access Journal Cancers in which they assessed anticancer combination to treat neuroendocrine tumors (NETs) using in vitro models (2D + 3D cultures in BIOMIMESYS hydroscaffolds). A NET arises in the specialized cells of the neuroendocrine system, which have traits of Read more…
You may have noticed on our website: we have changed our logo this summer, and it is the most visible part of our strategic development. Of course, we are always experts in HCS and cell imaging but, for us, it is the perfect time to show our deep expertise in Read more…
In the continuity of our scientific reviews about the important roles of Hyaluronic Acid (HA) in extracellular matrix (ECM) and cell behavior, we herein present this recent review describing the structure – function relationship of HA. As an important polysaccharide of ECM, HA plays an important role in cell and Read more…
As we are involved in some very interesting projects, we have the chance to work with amazing specialists in many field. All these people help us to make the BIOMIMESYS® technology better, easier to use and well adapted to their work. We asked them to explain why they use BIOMIMESYS® Read more…
Abstract The ATP Binding Cassette transporter B1 (ABCB1) induces chemoresistance in osteosarcoma, because it effluxes doxorubicin, reducing the intracellular accumulation, toxicity, and immunogenic cell death induced by the drug. The ATP Binding Cassette transporter A1 (ABCA1) effluxes isopentenyl pyrophosphate (IPP), a strong activator of anti-tumor Vγ9Vδ2 T-cells. Recruiting this population Read more…
As many companies in France and in the world, the COVID-19 pandemic deeply affects our activities. For safety reasons, most of our work is now done remotely but we maintain essential activity in laboratories to take care of our cells and try to finish our ongoing customer studies. The situation Read more…
We will give a presentation next week (on Tuesday, 10th of March 2020) at the High-Content Cellular Imaging User meeting organized by our partner Molecular Devices, which will take place in Leiden (Netherlands). It is a great pleasure for us to attend the meeting, and to talk about the applications, Read more…
In this video, Dr Karim Si-Tayeb explains how he uses BIOMIMESYS® in his research. We want to thank him! You can find below the translation in French and English (and you can change captions on the video). English (French is below) Hi my name is Karim Si-Tayeb I’m a researcher at Read more…
Nathalie and Elodie will be present in Marseille for BioFit event next week! Indeed, HCS Pharma has a booth in Clubster NSL’s pavilion (number I20). Just stop by 🙂 It will be a pleasure to talk to you about the innovative 3D cell culture matrix BIOMIMESYS® and our related services Read more…
We were in Taiwan few weeks ago, invited by our partner Molecular Devices to talk about our skills in 3D cell culture, with our unique groundbreaking technology BIOMIMESYS® and our services for in vitro screening from cell assay development to picture and data analysis. It was also a perfect opportunity Read more…
Last week, our study director Elodie was in Rennes to participate in NutrEvent! We had a booth there, under NSL Clubster pavilion (Lille Northern France Health and Nutrition clubster). It was a pleasure for her to present our activities in imaging and our 3D cell culture products to the visitors! Read more…
Elodie is waiting for you on the first floor at Nutr’event 2019! HCS Pharma stand is n° D6/2, on Clubster NHL pavilion. She will be glad to discuss with you about: our in vitro tests for the objectivation of your claims on human cells (e.g. nutraceutical, dermocosmetic claims) our innovative Read more…
With more than 25 countries represented, NutrEvent is THE place to be for business and innovation in Food, Nutrition and Health. It will take place next week in Rennes congress centre (Couvent des Jacobins), on the 22nd and 22rd of October. Our stand will be on Eurasanté Pavilion (Level 1 Read more…
We are very happy to share with you about HCS and 3D in vitro models thanks to a labroots.com webinar on October 27, 2019! This webinar is made with our partner Molecular Devices and it will present you many tips on how to handle 3D cell culture systems such as Read more…