New article published for Nanostem project about the interaction between nanoparticles and the blood-brain barrier in vitro

To treat brain disease is a challeging purpose, since the brain is protected by a barrier made by of tightly-joined endothelial cells of the cerebral microvessels, called the blood–brain barrier (BBB). To improve this route to reach the central nervous system, several strategies have been developed. Among them, researchers try Read more…

New 3D iPSC-derived brain endothelial cell model (Faley, Niel, et al. 2019)

The neurovasculaire unit (NVU) is composed of brain microvascular endothelial cells (BMECs) that form the Blood-Brain-Barrier (BBB), pericytes, neurons and glial cells. It regulates substance transport between blood and brain. BBB and NVU dysfonctions are associated with numerous neurological pathologies. Animal models are traditionally used in medical research but the Read more…

What’s new about Blood Brain Barrier? Feedback from the annual Congress of the SEISC

The annual meeting of the Society for the Study of Blood Brain interface (SEISC) took place in Paris the 9th November 2018. All day long, recent studies adressing different BBB issues have been presented, including Blood-Brain Barrier (BBB) development, molecular control, and several pathological aspects. BBB development: The meeting started Read more…