Posters
Poster – Urine sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia
Human induced pluripotent stem cells (hiPSC) are becoming a relevant model for the study of liver metabolic diseases once differentiated into hepatocyte-like cells (HLC), and it has been shown that they can faithfully recapitulate autosomal dominant hypercholesterolemia (ADH). PCSK9 is a critical modulator of cholesterol homeostasis, and quickly became a Read more…
HCS, HCA & Biology
Assessing GPCRs signaling using fluorescent bioscensors
Near half of the current drugs target GPCRs signaling !
HCS, HCA & Biology
High troughput in HCS in whole organism is the future?
Complexify cell models to improve relevance of the phenotyic assay in order to find new drugs more efficient is that’s what everyone strives to do.