Hepatotoxicity testing in animals predicts only 50% of liver damage observed in clinical context, in part, because of difference in inter-species hepatic metabolism (1). Therefore, a relevant in vitro model mimicking the micro-environment of the human liver for maintaining and promoting hepatocyte functions, is needed for a better hepatotoxicity prediction Read more…
When Tuesday, March 23, 2021 – 1PM (CET) / 8PM (CST) / 9PM (JST) / 7AM (EST) Thursday, March 25, 2021 – 9AM (CET) / 4PM (CST) / 5PM (JST) / 3AM (EST) Where Online, using zoom.us and live on Youtube What 3D cell culture systems have recently emerged as promising tools Read more…
Ask for high quality link by putting your email below We previously showed that human pluripotent stem cells (hiPSCs) provide a suitable model to study metabolic diseases upon hepatocyte-like cell (HLC) differentiation. In particular, HLCs have been used to model cholesterol metabolism regulation, by mimicking the main disease features in Read more…
We previously showed that human pluripotent stem cells (hiPSCs) provide a suitable model to study metabolic diseases upon hepatocyte-like cell (HLC) differentiation. In particular, HLCs have been used to model cholesterol metabolism regulation, by mimicking the main disease features in vitro. Human iPSCs can be generated from urine samples of Read more…