Dans le cadre de notre développement, nous recrutons un(e) Technicien(ne) en recherche et développement axée sur des modèles hépatiques in vitro. Vous serez en charge de : Gestion du laboratoire (commandes, entretien des machines, règles HSE, gestion des stocks) Maintien des cultures cellulaires en routine (lignées, cellules primaires, cellules souches, etc…) Read more…
Ask for high quality link by entering your email below Hepatocytes in primary cultures are still the gold standard in the pharmaceutical industry ; however they are expensive and have a very short lifespan with a progressive loss of specific functions over time. The dipolar aprotic solvent, dimethyl sulfoxide (DMSO) Read more…
This year, the ESTIV (European Society of Toxicology In Vitro) congress took place in Berlin and was again a very interesting symposium. The plenary session was open by a presentation on 3D models made by bioengineering made by Paula Alves (Oireas/PT), and this year, a lot of presentations and poster were Read more…
Many categories of drugs can induce hepatotoxicity, so improving the prediction of toxic drugs is important. In vitro models using human hepatocytes are more accurate than in vivo animal models. Good in vitro models require an abundance of metabolic enzyme activities and normal cellular polarity. However, none of the in Read more…
We had the pleasure to attend ELRIG Fr meeting in Bischoffsheim (near Strasbourg) on the 23-24th of May. There we enjoyed meeting our partners Molecular Devices and Integra biosciences, and seeing great presentations about the last trends in automation. Our collaborator Karim Si-Tayeb presented his amazing results regarding the differentiation Read more…
Cell-based high-content screening (HCS) assays have become an increasingly attractive alternative to traditional in vitro and in vivo testing in pharmaceutical drug development and toxicological safety assessment.