HCS, HCA & Biology
Induced pluripotent stem cells (iPSCs) to improve early detection of drug neurotoxicity
One third of the safety failures is linked to CNS toxicity during the clinical trials of drugs. In order to develop a more predictable in vitro human model for neurotoxicity testing, we have compared the sensibility of iPSC-derived neuronal cells and SH-SY5Y cell line (neuroblastoma-derived cell line) to a panel Read more…