Wound healing is a crucial physiological process rehabilitating the unity of the skin barrier. Inflammation in wound healing is a weapon with two edges. It is indispensable but must be strongly regulated both temporally and spatially. In this recent study, Li et al. show skin commensal S. epidermidis produces a Read more…
Skin commensals are crucial in the maintenance of the epithelial barrier function, regulation of the host immune system, and prevent invasion of other pathogenic microbes. In this article, published in September 2018, Burmeister et al show that Staphlylococcus, Streptococcus, Pseudomonas, Corynebacterium, and anaerobes have both beneficial and harmful effects depending Read more…
Large number of visitors came to Cosmet’agora last week to discover the last innovations in cosmetic formulation. It was a great opportunity to discuss with leader companies developing active ingredients and to feel emerging trends in the cosmetic market: microbiota balance preservation and chronobiology in particular. Our fully automatic wound Read more…
Wounds can exhibit impaired healing, as a consequence of pathologic failure to process one of the normal stage of healing. Wound healing impairment could be characteristic of the treatments of chronic wounds due to immobilisation, diabetes, and skin infection. Characterization of compounds efficacy on wound healing parameters is important dermato Read more…
Cell biology is part of the R&D activity in dermocosmetology. At HCS Pharma, we are developing dermocosmetology assay using our automation platform and high content analysis software.
To find anti-cancer drugs, different cellular modifications can be looked at: cell death effect on proliferating cells either in 2D culture or on spheroids (3D culture), anti-mitotic, anti-migration/invasion, anti-angiogenesis effects… Different assays can be performed to follow these different effects. High content screening is a multi-parametric technology allowing searching for poly-effects drugs.
This summer has been very studious for us with the development and validation of new tests in the oncology field.