What is BIOMIMESYS® hydroscaffold?
BIOMIMESYS® is a unique groundbreaking 3D cell culture technology which associates the behavior of a solid scaffold and of a hydrogel which provide a cell culture microenvironment reproducing all aspects of human tissues, including matrix architecture, cellular organization, cell-cell and cell-matrix interactions.
Depending on the organ , extracellular matrix components may vary as well their proportions, allowing a more or less dense and compact cellular environment (different Elastic Modulus, porosity).
BIOMIMESYS® matrices are made of Hyaluronic Acid (HA), the main glycosaminoglycan (GAG) of the ECM, collagens and adhesion proteins. Our patented manufacturing process allow preserving the natural properties of HA and therefore synthesizing proprietary Hydroscaffold™.
Tuning the composition of BIOMIMESYS® matrix allows mimicking the cellular microenvironment of organ or tissue of interest.
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The physicochemical properties of the extracellular matrix (ECM) in which cells reside have emerged as an important regulator of cell behavior. To mimic the ECM, we need to know the physicochemical properties (mechanical & composition) in normal and pathological organs.