BIOMIMESYS® is a unique groundbreaking 3D cell culture technology which associates the behavior of a solid scaffold and of a hydrogel. It provides a cell culture microenvironment reproducing all aspects of human tissues, including matrix architecture, cellular organization, cell-cell and cell-matrix interactions.
Depending on the organ, extracellular matrix components and their proportions may vary, allowing a more or less dense and compact cellular environment (different Elastic Moduli, porosities).
BIOMIMESYS® matrices are made of Hyaluronic Acid (HA), the main glycosaminoglycan (GAG) of the ECM, collagens and adhesion proteins. Our patented manufacturing process allows to preserve the natural properties of HA and therefore synthesizing proprietary Hydroscaffold™.
Tuning the composition of BIOMIMESYS® matrix allows to mimic the cellular microenvironment of any organ or tissue of interest.
BIOMIMESYS® Adipose Tissue
HA + RGDS
Elastic Modulus: 0.5 kPa
Cells already tested
Primary human cells: Human White Adipocytes (Subcatenous)
- 3T3-L1 mouse preadipocytes
- 3T3-F442A mouse preadipocytes
- iPSC-derived human adipocytes
For a better differentiation and cell longevity
BIOMIMESYS® Adipose Tissue is dedicated to the culture of adipocytes: compared to 2D culture, primary human pre-adipocytes in BIOMIMESYS® Adipose Tissue (3D) showed optimal differentiation into adipocytes, and their functionality (such as lipid storage in a single large vacuole) was maintained until 28 days!