In HCS Pharma we strongly believe that 3D cell culture is the right way to improve drug dicovery processes. Moreover, we know that our 3D hydroscaffold matrix BIOMIMESYS® could be useful for bioproduction and then for cell therapy. We will be happy to meet you at ELRIG congress “Advancements in cell & Read more…
This year, InnaSCo and Frontinov propose a joint scientific meeting dealing with inflammation, including presentations of prestigious speakers. This meeting will take place next week as a 2-day webinar, on the 20th and 21st October. The first day will be dedicated to quantitative biology approaches for exploration of inflammatory responses. This part of the Read more…
As you might know, October is the Breast Cancer Awareness Month, an annual campaign to raise awareness about the impact of breast cancer. Research is the key tool to fight this disease and we are very happy to collaborate with amazing research teams in this fight. Since last year, our Read more…
Pharmaceutical industry is facing a very high failure rate in drug discovery, with 90% of failure in clinical trials. This is particularly true for central nervous system applications, with a rate of 30% safety failure in clinical trials, compared to 7% in preclinical trials (Cook et al. 2014). This reveals Read more…
When Tuesday, June 1, 2021 – 1PM (CET) / 8PM (CST) / 9PM (JST) / 7AM (EST) Thursday, June 3, 2021 – 9AM (CET) / 4PM (CST) / 5PM (JST) / 3AM (EST) Where Online, using zoom.us and live on Youtube What Pharmaceutical industry is facing a very high failure rate in Read more…
Cultivated meat is meat produced from cells cultures, and it appears as a promising alternative to traditional meat derived from animals. Sometimes known as clean meat, cultured meat or in vitro meat, such cells are cultured in a customizable and controlled platform. The manipulation, enhancement as well as adaptation of Read more…
This summer, Vitali et al. published an article in the Open Access Journal Cancers in which they assessed anticancer combination to treat neuroendocrine tumors (NETs) using in vitro models (2D + 3D cultures in BIOMIMESYS hydroscaffolds). A NET arises in the specialized cells of the neuroendocrine system, which have traits of Read more…
Stroke is the second leading cause of death worldwide and the most common cause of disability in adults. Ischemic stroke represents 80% of the cases. They cause oxygen and glucose deficit in the brain, leading to necrosis, edema formation, inflammation and apoptosis. Endogenous repair mechanisms, like cerebral plasticity, limit ischemia-linked Read more…
The extracellular matrix (ECM) is a three-dimensional macromolecular network composed of structural proteins (collagens, elastin), adhesion/signalling proteins (fibronectin, laminins), different proteoglycans, glycoproteins and glycosaminoglycans (GAGs). GAGs are structurally complex, but their structure is simply made up of repeating disaccharide building blocks composed of alternating uronic acid and hexosamine units. GAGs Read more…
Sood et al. published in 2016 an interesting article about the effect of extracellular matrix (ECM) on in vitro neuronal cells culture: “Fetal brain extracellular matrix boosts neuronal network formation in 3D bioengineered model of cortical brain tissue “. The aim of the study was to study the effects of Read more…
We are developing a new BIOMIMESYS® hydroscaffold for neuronal cells. First results are very promising because neurons grow and form neurites. Moreover cells lived longer than in monolayer culture. We are currently finalizing this new hydroscaffold to find the best conditions of 3D neuron culture, but BIOMIMESYS® Brain will be soon Read more…
Our new poster on BIOMIMESYS® technology is now avalaible on this link. It presents the use of this scaffold on our automated platform (Hapix), with the development of a 3D cell model for steatosis and phospholipidosis assessment as an example. Automated HepG2 cells seeding, medium renewal, spheroids treatment, fixation, staining and Read more…
