The extracellular matrix (ECM) is known as a molecular network of macromolecules present in all solid tissues (Figure 1), which plays an important role in the growth, migration and differentiation of cells. This ECM is part of a complex and plastic microenvironment in health and disease: its composition and physical Read more…
There are many things to perform today using Artificial Intelligence (AI), especially in health and drug discovery domains (but only if you understand the technologies!). If you want to improve your knowledge in the field during the summer, I recommend you read the “AI, ML & Deep learning Community of Read more…
We were invited at the workshop organized by SMILL-E (Seeding Microsystems in Medecine in Lille – European-Japanese Technologies against Cancer) and Yncrea during MedFit event last week. This great workshop was about Digital and Micro systems for LifeTECH. Elodie was there to talk about innovative technologies for the screening of Read more…
Atopic dermatitis (AD) is a chronic, common inflammatory skin disease affecting 15-20% of children and 1-3% of adults worldwide. Loss of bacterial diversity from excess abundance of Staphylococcus aureus is associated with increased disease severity, nevertheless, how dysbiosis of the skin microbiome may influence atopic dermatitis pathophysiology is unknown. In Read more…
It was a great pleasure to be invited (thanks to our partner Molecular Devices) to present our work during these 2 events organized by selectBio in Rotterdam: Organoids and Tox Screening Europe 2019 on June 13-14 Organ-on-a-Chip and Tissue-on-a-Chip Europe 2019 on June 18-19 Both were of great interest for Read more…
Elodie, Véronique et Océane ont profité d’un moment très sympathique – et ensoleillé – lors du barbecue du parc Eurasanté ce midi… Merci à tous, et bon week-end 🙂
In the continuity of our scientific reviews about the important roles of Hyaluronic Acid (HA) in extracellular matrix (ECM) and cell behavior, we herein present this recent review describing the structure – function relationship of HA. As an important polysaccharide of ECM, HA plays an important role in cell and Read more…
Last week we were pleased to attend the founding congress of STCM (Société de Toxicologie Cellularie et Moléculaire), which was held in FIAP Jean Monnet (Paris). The topic was “Toxicology towards the 3rd dimension“. With a wide variety of talks from academic laboratories and from the industry, the content was Read more…
The founding congress of the french STCM (Société de Toxicologie Cellulaire et Moléculaire) will take place in Paris at the end of this week (13th-14th June, 2019). The theme of this meeting will be “Toxicology towards the 3rd dimension“. We are looking forward to attending this congress, and to becoming Read more…
We will be present this week and next week in Rotterdam, to talk about 3D cell culture and the importance of the microenvironnement in the relevance of in vitro models. As you known, to mimic human tissues, several parameters need to be taken into account: the target cells, nutrient intake Read more…
The extracellular matrix (ECM) is a three-dimensional macromolecular network composed of structural proteins (collagens, elastin), adhesion/signalling proteins (fibronectin, laminins), different proteoglycans, glycoproteins and glycosaminoglycans (GAGs). GAGs are structurally complex, but their structure is simply made up of repeating disaccharide building blocks composed of alternating uronic acid and hexosamine units. GAGs Read more…
Even if microbiota-relateds treatments are quite recent in the therapeutical field, at least 2,400 clinical trials were launched in 2018! Gut, skin and oncology microbiota will be definitively be the hot topic in the next 10 years. Of course, we are heavily working in the field, with a focus on Read more…
The 16th SFBMEC congress was held last week in Reims: Elodie and Zied attended the meeting to be aware of the last trends in extracellular matrix (ECM) research and industry and medical applications. And they were not disappointed! After a first touching lecture in memoriam of the late Ladislas Robert Read more…
Our CDO Grégory was at the Fluorescence Microscopy Worskshop last week at Pasteur Paris to discover new usages and technologies in microscopy. Even if this event was mainly focused on super resolution microscopy, many tips and tools proved useful in HCS context, where speed and statistical results are often more Read more…
Our study director Elodie really enjoyed Vitafoods last week in Geneva, and the welcome she had on the different booths she visited along the three days! The show was very impressive, with a wide variety of exhibitors (more than 1.000 companies) and more than 20.000 visitors! Elodie spent much time Read more…
Ask for high quality link by putting your email below The extracellular matrix (ECM) is present in all solid tissues and is a master regulator of cell behavior and phenotype. The ECM in each tissue is characterized by its biochemical and biophysical properties, which are modified in many different types Read more…
Next week HCS Pharma will be present at SFBMEc Reims (15th-17th May). We will present a poster about the influence of BIOMIMESYS® hydroscaffold composition and stiffness on the 3D culture of breast cancer cells. The poster will be avalaible next week, but if you want it before, you can contact Read more…
You should know Science Exchange, the world’s leading and most secure platform for outsourced research, providing large R&D organizations with the fastest path from discovery through development and commercialization. Now, we are very proud to provide our most innovative services on the platform! We will find: 3D Cell Culture Models Read more…
We will be at Vitafoods Europe 2019 next week in Geneva. It’s a big opportunity to discover our services in nutraceticals and dermocosmetology. This year Vitafoods Europe will focus on sustainability, it’s why we will emphasis the presentation of our completely physiological BIOMIMESYS® hydroscaffold for 3D cell culture. We will Read more…
Many skin diseases, including psoriasis and basal cell carcinoma, are associated with microbial dysbiosis characterized by reduced C. acnes prevalence. C. acnes is a facultative anaerobic bacterium that is frequently found on the human skin. This bacterium is both an opportunistic pathogen and a commensal organism. Indeed, most individuals are Read more…
The California Cruelty-Free Cosmetics Act, SB 1249, was introduced in the California State Legislature. On Jan. 1st, 2020 the bill will prohibit the sale of animal-tested cosmetics in the state. The European Union ended importation and sale of any new cosmetics that have been tested on animals in 2013 with Read more…
Last week HCS Pharma team enjoyed Forum Labo Paris! We enjoyed it twofold because : we won our booth on the Lab’StartUp Village, in the heart of the fair. It gave us the opportunity to present our BIOMIMESYS® products! we won a price for our amazing photo of liver cells… Read more…
The neurovasculaire unit (NVU) is composed of brain microvascular endothelial cells (BMECs) that form the Blood-Brain-Barrier (BBB), pericytes, neurons and glial cells. It regulates substance transport between blood and brain. BBB and NVU dysfonctions are associated with numerous neurological pathologies. Animal models are traditionally used in medical research but the Read more…